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上皮间质转化现象对瘢痕疙瘩临床治疗的意义

张明子 王晓军

组织工程与重建外科杂志2017,Vol.13Issue(3):121-122,2.
组织工程与重建外科杂志2017,Vol.13Issue(3):121-122,2.DOI:10.3969/j.issn.1673-0364.2017.03.001

上皮间质转化现象对瘢痕疙瘩临床治疗的意义

The Significance of Epithelium-to-Mesenchymal Transition in Keloid Treatment

张明子 1王晓军1

作者信息

  • 1. 100730 北京市 中国医学科学院北京协和医院整形美容外科
  • 折叠

摘要

Abstract

Keloid scar is a fibrogenesis tumor-like disease featured by invasion to the surrounding skin. Epithelium-to-mesenchymal transition (EMT) is a process which leads to the loss of epithelial cell polarity and cell-cell adhesion. Through the process of EMT, epithelial cells acquire migratory and invasive behavior and are thus able to transform into mesenchymal cells. EMT has a high clinical significance towards keloid treatment.

关键词

上皮间质转化/瘢痕疙瘩/治疗

Key words

Epithelium-to-mesenchymal transition/Keloid/Treatment

分类

医药卫生

引用本文复制引用

张明子,王晓军..上皮间质转化现象对瘢痕疙瘩临床治疗的意义[J].组织工程与重建外科杂志,2017,13(3):121-122,2.

组织工程与重建外科杂志

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1673-0364

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