癌变·畸变·突变2017，Vol.29Issue(4)：260-265,6.DOI:10.3969/j.issn.1004-616x.2017.04.004
电子垃圾拆解区人群甲状腺激素水平改变的 Meta分析
Meta-analysis on thyroid hormone levels of populations frome-waste dismantling regions
摘要
Abstract
OBJECTIVE:To evaluate correlations between serum thyroid hormone levels and exposure to toxic substances from e-waste dismantling regions.METHODS:Randomized-control studies on correlations between serum thyroid hormone levels and exposure to toxic substances from e-waste dismantling areas that were reported on PubMed, Web of Science,Elsevier,CNKI and WanFang Database up to April 2017 were searched and analyzed. The data of the included studies were analyzed using Revman 5.2.RESULTS:9 randomized-controlled studies were identified including 489 people exposed to toxic chemicals from e-waste dismantling areas and 489 people of control. Serum 1evels of total thyroxine (T4) and free thyroxine (FT4) in the expose groups were significantly lower than those in the control groups (P<0.05),while there were no significant differences in the serum levels of free triiodothyronine (FT3),total triiodothyronine (T3) and thyrotropin (TSH)(P>0.05).CONCLUSION:Exposed to toxic chemicals from e-waste dismantling regions may affect the serum level of thyroid hormone.关键词
电子垃圾拆解区/人群/甲状腺激素/Meta分析Key words
e-waste dismantling region/human/thyroid hormones/Meta-analysis分类
医药卫生引用本文复制引用
唐光媛,刘冉,余小金..电子垃圾拆解区人群甲状腺激素水平改变的 Meta分析[J].癌变·畸变·突变,2017,29(4):260-265,6.基金项目
国家自然科学基金项目(81573108) （81573108）
国家"十二五"水专项课题(2014ZX07405002) （2014ZX07405002）
江苏省普通高校研究生科研创新计划资助项目(SJZZ150023) （SJZZ150023）
