癌变·畸变·突变2017,Vol.29Issue(4):313-315,3.DOI:10.3969/j.issn.1004-616x.2017.04.014
5种塑胶跑道面层的体外细胞毒性
实验检测
In vitro cytotoxicity tests of five plastic
runway surface materials
李敏 1黄宇锋 1刘冬虹 1郭新东 1陈汉金 1庞增雄 1江漪 1刘香梅1
作者信息
- 1. 广州质量监督检测研究院,广东 广州511447
- 折叠
摘要
Abstract
OBJECTIVE:To investigate toxicity of extracts from five kinds of plastic runway surface layer (silicon PU ball surface layer,plastic mat,EPDM plastic track,mixed plastic runway panel,prefabricated plastic track) and to provide a preliminary understanding of its safety to mouse fibroblast L-929.METHODS:Four groups of high density polyethylene negative control,no sample blank control,10% DMSO positive control and 0.5% DMSO extract were used to detect the cytotoxicity of the sample extract on mouse fibroblast L-929 using XTT colorimetry.RESULTS:The relative proliferation rate of the four kinds of samples of silicon PU ball surface layer,plastic mat,EPDM plastic track and mixed plastic runway panel was less than 70%. The relative proliferation rate of the prefabricated plastic runway sample was more than 70%.CONCLUSION:0.5% DMSO extract showed strong in vitro cytotoxicity of silicon PU ball surface layer, plastic mat,EPDM plastic track,mixed plastic runway panel sample.关键词
塑胶跑道/体外细胞毒性/二甲基亚砜/XTT染色检测Key words
plastic runway/invitro cytotoxicity/dimethylsulfoxide/XTT staining分类
医药卫生引用本文复制引用
李敏,黄宇锋,刘冬虹,郭新东,陈汉金,庞增雄,江漪,刘香梅..5种塑胶跑道面层的体外细胞毒性
实验检测[J].癌变·畸变·突变,2017,29(4):313-315,3.