安徽农业科学2017，Vol.45Issue(16)：97-101,137,6.
比较岩藻黄素·灵芝孢子粉和黑枸杞对小鼠酒精性脂肪肝的影响
Comparison of the Effects of Fucoxanthin, Ganoderma lucidum Spore Powder and Lycium ruthenicum on Alcoholic Fatty Liver in Mice
摘要
Abstract
[Objective] The research aimed to discuss the effects of fucoidan,Ganoderma lucidum spore powder and Lycium ruthenicum on alcoholic fatty liver in mice.[Method] NIAAA mouse alcohol liver model was established.10 week-old male C57BL/6 mice were randomly divided into control group,model group,100 mg/(kg · d) fucoxanthin group,500 mg/(kg · d) Ganoderma lucidum spore powder group and 500 mg/(kg · d) Lycium ruthenicum group.At the end of experiments,liver tissue was weighed,liver index of each group was compared,and some liver tissues were taken for histopathological observation.The contents of serum alanine transaminase (ALT),aspartate transaminase (AST),triglyceride (TG),cholesterol (TC),liver triglyceride (TG) were measured by the commercial kit.[Result] Compared with the model group,fucoxanthin inhibited the alcohol-induced steatosis and reduced the contents of serum ALT,AST,TG and liver TG.Ganoderma lucidum spore powder to effectively relieve the serum ALT,AST content increased,but did not effectively inhibit the alcohol-induced steatosis.While Lycium ruthenicum suppressed alcohol-induced steatosis,but did not significantly alleviate the serum ALT,AST increased.[Conclusion] Compared with Ganoderma lucidum spore powder and Lycium ruthenicum,fucoidin can cause alcohol damage and steatosis to play a better protective effect.关键词
酒精性脂肪肝/岩藻黄素/灵芝孢子粉/黑枸杞Key words
Alcoholic fatty liver/Fucoxanthin/Ganoderma lucidum spore powder/Lycium ruthenicum分类
农业科技引用本文复制引用
臧瑾,何钊..比较岩藻黄素·灵芝孢子粉和黑枸杞对小鼠酒精性脂肪肝的影响[J].安徽农业科学,2017,45(16):97-101,137,6.基金项目
国家自然科学基金项目(31471321). （31471321）
