安徽医科大学学报2017，Vol.52Issue(7)：1085-1087,3.DOI:10.19405/j.cnki.issn1000-1492.2017.07.033
RASAL2在乳腺癌中的表达及临床意义
Expression of RASAL2 in breast cancer and its clinical significance
摘要
Abstract
The expression of Ras protein activator like 2(RASAL2)was detected by immunohistochemistry in 60 samples of breast cancer tissues and adjacent paracancerous tissues.The correlation between RASAL2 expression and clinicopathological characteristics was analyzed.The present data showed that the expression of RASAL2 in breast cancer tissue was significantly lower than that in adjacent paracancerous tissue (χ2=25.145,P<0.001).The expression of RASAL2 in Luminal B breast cancer was significantly lower than that in Non-Luminal B breast cancer (χ2=4.319,P=0.038).The expression level of RASAL2 was correlated with ER, PR expression,lymph node metastasis, TNM stage and vascular invasion (P<0.05).The expression of RASAL2 is obviously decreased in breast cancer tissue than in adjacent paracancerous tissue, and its low expression is correlated with the development and metastasis of breast cancer.关键词
乳腺癌/RASAL2/免疫组化Key words
breast cancer/RASAL2/immuneohistochemistry分类
医药卫生引用本文复制引用
穆婧,汤铜,钱波,郑璐,童婷婷..RASAL2在乳腺癌中的表达及临床意义[J].安徽医科大学学报,2017,52(7):1085-1087,3.基金项目
安徽省自然科学基金(编号:1308085QH152) （编号:1308085QH152）
安徽医科大学校科研基金联合资助项目(编号:2015xkj111) （编号:2015xkj111）
