川北医学院学报2017，Vol.32Issue(3)：336-338,3.DOI:10.3969/j.issn.1005-3697.2017.03.006
普米克令舒联合孟鲁司特对慢性阻塞性肺疾病急性加重期的疗效分析
Clinical efficacy of pulmicort and montelukast in the treatment of acute exacerbation of chronic obstructive pulmonary disease
摘要
Abstract
Objective:To analyze the clinical efficacy of pulmicort and montelukast in the treatment of acute exacerbation of chronic obstructive pulmonary disease (AECOPD).Methods:Clinical data of patients with AECOPD received treatment in our hospital were analyzed.According to different therapy,the enrolled patients were divided into two groups,observation group(pulmicort and montelukast,n=58) and control group (pulmicort,n=51).The curative effect of the two groups were compare 7 days after treatment.Results:After treatment,patients in the observation group had lower scores of CPIS and Borg than these in the control group,the in-hospital mortality and level of PaCO2 in the observation group were lower than these in the control group, and the level of PaO2 was higher in the observation group.After treatment,levels of peripheral blood monocyte chemoattractant protein-1 and interleukin-6 reduced both in the observation group and control group,and the level in the observation was lower than that in the control group,the difference was statistically significant (P<0.05).Conclusion:Pulmicort combined with montelukast can significantly improve the clinical efficacy in the treatment of AECOPD,which associated with its anti-inflammatory action.关键词
慢性阻塞性肺疾病急性加重期/普米克令舒/孟鲁司特/疗效Key words
Acute exacerbation of chronic obstructive pulmonary disease/Pulmicort/Montelukast/Efficacy分类
医药卫生引用本文复制引用
王立,梁莉萍..普米克令舒联合孟鲁司特对慢性阻塞性肺疾病急性加重期的疗效分析[J].川北医学院学报,2017,32(3):336-338,3.基金项目
三亚市科技工业信息化局资助课题(YW1331) （YW1331）
