韩铮 1刘爱连 1刘泽群 1陈丽华 1汪禾青 1孙美玉 1宋清伟1
作者信息
- 1. 大连医科大学附属第一医院放射科,大连 116000
- 折叠
摘要
Abstract
Objective: To evaluate the feasibility of the monoexponential model of diffusion-weighted imaging (DWI), biexponential and stretched-exponential models of intravoxel incoherent motion (IVIM) and to compare the optimization in these models in differentiating hepatocellular carcinoma (HCC) from hepatic hemangioma (HH). Materials and Methods: Sixty-six patients under MR liver scanning were retrospectively enrolled in our hospital. All the patients were performed MRI exams on a 1.5 T scanner. For each region of interested (ROI), the mean values of DWI (ADC), eDWI (Standard ADC, D-mono, D*-mono, fmono, D-Bi、D*-Bi、fBi) and HB DWI (DDC, α) were measured. Results: The ADC, Standard ADC, D-mono, D*-mono, fmono, D-Bi, D*-Bi, fBi, DDC values of HCC and HH were statistically significant (P<0.05). The area under the ROC curve of ADC, Standard ADC, D-mono, fmono, D-Bi were higher than 0.9. The differential diagnostic efficiency with Standard ADC were significantly better than ADC. The differential diagnostic efficiency with ADC was significantly better than D*-Bi, fBi, HB DDC. Conclusions: The values of ADC, Standard ADC from monoexponential model, D-mono, fmono, D-Bi from double monoexponential model have favorable effective functions for the diagnosis, Standard ADC from monoexponential model with multiple b values were significantly better than ADC from monoexponential model with single b value in differential diagnosis of hepatocellular carcinoma and hepatic hemangioma.关键词
肝肿瘤/弥散磁共振成像/体素不相干运动成像/双指数模型/拉伸指数模型Key words
Liver neoplasms/Diffusion magnetic resonance imaging/Intravoxel incoherent motion/Biexponential model/Stretched-exponential model分类
医药卫生
