重庆医学2017，Vol.46Issue(19)：2677-2682,6.DOI:10.3969/j.issn.1671-8348.2017.19.025
首次卒中患者卒中部位与卒中后抑郁相关性的Meta分析
The Relationship between stroke location and post-stroke depression in first-ever stroke patients:a Meta-analysis
温尊甲 1吴超 2沈梅芬 1梅彬彬 1丁建平2
作者信息
- 1. 苏州大学第一附属医院神经外科,江苏苏州215002
- 2. 苏州大学护理学院,江苏苏州215002
- 折叠
摘要
Abstract
Objective To systematically evaluate the relationship between stroke location and post-stroke depression (PSD) in first-ever stroke patients.Methods The studies on the relationship between stroke location and PSD published from January 1980 to March 2016 were retrieved from databases,including Chinese science and technology journal full-text database (VIP),China journal full-text database (CNKI),Wanfan database,PubMed,ISI Web of Science,Ovid database and Elsevier Science Direct.RevMan5.3 software was adopted for data consolidation and analysis.Results A total of 14 studies,including 1 952 cases of patients were included.The meta analysis indicated that no direct relationship was found between stroke location and PSD in first-ever stroke patients [random effects model,95 ％CI(0.89,1.43),P＜0.01].The results of subgroup analysis indicated that the PSD was associated with the right hemisphere lesion when the Hamilton Depression Scale (HAMD) was adopted for assessment [fixed effects model,95 ％ CI(1.21,1.76),P＜0.01],while the relationships were not found in the subgroup analysis of time course after stroke and the aphasia occurrence.Conclusion Stroke location may be not directly associated with PSD,further studies are needed to ascertain the relationship between stroke location and PSD.关键词
卒中/抑郁/卒中部位/相关性/Meta分析Key words
stroke/depression/stroke location/correlation/Meta-analysis分类
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温尊甲,吴超,沈梅芬,梅彬彬,丁建平..首次卒中患者卒中部位与卒中后抑郁相关性的Meta分析[J].重庆医学,2017,46(19):2677-2682,6.
