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GCH1 plays a role in the high-altitude adaptation of Tibetans

Yong-Bo GUO Cai-juan Bai Gonggalanzi Yong-Yue Pan Qula Kangmin Cirenyangji Baimayangji Wei Guo Yangla Hui Zhang Yao-Xi He Xiao-Ming Zhang Wang-Shan Zheng Shu-Hua Xu Hua Chen Sheng-Guo Zhao Yuan Cai Shi-Ming Liu Tian-Yi Wu Xue-Bin Qi Bing Su Chao-Ying Cui Ouzhuluobu Baimakangzhuo Duojizhuoma Dejiquzong Bianba Yi Peng

动物学研究2017，Vol.38Issue(3)：155-162,8.
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动物学研究2017，Vol.38Issue(3)：155-162,8.DOI:10.24272/j.issn.2095-8137.2017.037

GCH1 plays a role in the high-altitude adaptation of Tibetans

GCH1 plays a role in the high-altitude adaptation of Tibetans

Yong-Bo GUO 1Cai-juan Bai 2Gonggalanzi 3Yong-Yue Pan 3Qula 3Kangmin 3Cirenyangji 3Baimayangji 3Wei Guo 3Yangla 3Hui Zhang 3Yao-Xi He 2Xiao-Ming Zhang 2Wang-Shan Zheng 4Shu-Hua Xu 2Hua Chen 1Sheng-Guo Zhao 2Yuan Cai 5Shi-Ming Liu 6Tian-Yi Wu 7Xue-Bin Qi 8Bing Su 1Chao-Ying Cui 1Ouzhuluobu 9Baimakangzhuo 9Duojizhuoma 2Dejiquzong 2Bianba 3Yi Peng3

作者信息

  • 1. College of Animal Science and Technology, Gansu Agricultural University, Lanzhou Gansu 730070, China
  • 2. State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming Yunnan 650223, China
  • 3. High Altitude Medical Research Center, School of Medicine, Tibetan University, Lhasa Tibet 850000, China
  • 4. Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming Yunnan 650204, China
  • 5. Chinese Academy of Sciences Key Laboratory of Computational Biology, Max Planck Independent Research Group on Population Genomics, CAS-MPG Partner Institute for Computational Biology(PICB), Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China
  • 6. School of Life Science and Technology, Shanghai Tech University, Shanghai 200031, China
  • 7. Collaborative Innovation Center of Genetics and Development, Shanghai 200438, China
  • 8. Center for Computational Genomics, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China
  • 9. National Key Laboratory of High Altitude Medicine, High Altitude Medical Research Institute, Xining Qinghai 810012, China
  • 折叠

摘要

关键词

GCH1/Positive selection/Tibetan/Hypoxia adaptation/Nitric oxide/Hemoglobin/Oxygen saturation

Key words

GCH1/Positive selection/Tibetan/Hypoxia adaptation/Nitric oxide/Hemoglobin/Oxygen saturation

引用本文复制引用

Yong-Bo GUO,Cai-juan Bai,Gonggalanzi,Yong-Yue Pan,Qula,Kangmin,Cirenyangji,Baimayangji,Wei Guo,Yangla,Hui Zhang,Yao-Xi He,Xiao-Ming Zhang,Wang-Shan Zheng,Shu-Hua Xu,Hua Chen,Sheng-Guo Zhao,Yuan Cai,Shi-Ming Liu,Tian-Yi Wu,Xue-Bin Qi,Bing Su,Chao-Ying Cui,Ouzhuluobu,Baimakangzhuo,Duojizhuoma,Dejiquzong,Bianba,Yi Peng..GCH1 plays a role in the high-altitude adaptation of Tibetans[J].动物学研究,2017,38(3):155-162,8.

基金项目

This study was supported by grants from the Strategic Priority Research Program of the Chinese Academy of Sciences (XDB13010000),the National Natural Science Foundation of China (91631306 to BS,31671329 to XQ,31460287 to Ou.,31501013 to HZ and 31360032 to CC),the National 973 program (2012CB518202 to TW),the State Key Laboratory of Genetic Resources and Evolution (GREKF15-05,GREKF16-04),and the Zhufeng Scholar Program of Tibetan University （XDB13010000）

动物学研究

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