国际病理科学与临床杂志2017，Vol.37Issue(5)：889-894,6.DOI:10.3978/j.issn.2095-6959.2017.05.003
经颈静脉肝内门体静脉分流术对脾切除术后门静脉高压患者治疗的有效性与安全性
Effect and safety of transjugular intrahepatic portosystemic shunt on treatment of patients with portal hypertension after splenectomy
沈能 1田旭 1黄鹤 2陈伟庆 1褚建国2
作者信息
- 1. 重庆市肿瘤研究所/医院/癌症中心消化内科,重庆400030
- 2. 中国人民解放军空军总医院放射科,北京100142
- 折叠
摘要
Abstract
Objective:To explore the effects and safety of transjugular intrahepatic portosystemic shunt (TIPS) on patients with portal hypertension after splenectomy.Methods:Sixty-eight patients with portal hypertension after splenectomy undergoing TIPS during May 2005 to May 2010 in Department of Radiation of Air Force General Hospital of PLA were enrolled into case group,and those patients with portal hypertension undergoing TIPS alone were recruited as control group.And eventually,we will analyze the success rate of operation,liver function,count ofplatelets and portal pressure before and after undergoing operation,and the adverse events between these two groups.Results:The success rates of operation in case and control groups were 97.06％ (66/68) and 100％(68/68) respectively,with statistical significance (xG0.04,P=0.15).The liver function and counts of platelets in these two groups before and after undergoing operation were not statistically significantly different (P＞0.05),however the counts of platelets in these groups decreased to be 45.4±8.6 and 59.4±15.8,the differences in each group was statistical significant (P＜0.05).The ALB in case group decreased to be 29.8±6.3,with statistical significance (P＜0.05).The portal pressure in these two groups decreased to be 27.3±5.4 and 28.5±4.3,the differences in each group was statistical significant (P＜0.05).After follow-up of 12-60 months,the failure rate of shunt in case group was higher than that of control group (22.73％ vs.8.82％,P=0.04),and the rate of remaining adverse evets were not statistical significant.Conclusion:TIPS in treating patients with portal hypertension after splenectomy obtain expected efficacy,however the failure rate of shunt after operation should be controlled cautiously when this operation option is considered.关键词
门静脉高压/上消化道出血/脾切除术/经颈静脉肝内门体分流术Key words
portal hypertension/upper gastrointestinal bleeding/splenectomy/transjugular intrahepatic portosystemic shunt引用本文复制引用
沈能,田旭,黄鹤,陈伟庆,褚建国..经颈静脉肝内门体静脉分流术对脾切除术后门静脉高压患者治疗的有效性与安全性[J].国际病理科学与临床杂志,2017,37(5):889-894,6.
