广西医科大学学报2017，Vol.34Issue(7)：1037-1040,4.DOI:10.16190/j.cnki.45-1211/r.2017.07.023
1.5 T MR扩散加权成像对前列腺癌诊断价值及其ADC值与Gleason评分、肿瘤标志物的相关性分析
The value of 1.5 T MR diffusion weighted imaging in the diagnosis of prostate cancer and the association between ADC and Gleason score and tumor markers
张勇1
作者信息
- 1. 江苏省南京市溧水区人民医院放射科,南京211200
- 折叠
摘要
Abstract
Objective:To study the diagnostic value of diffusion-weighted imaging in 1.5 T MR and the correlation between apparent diffusion coefficient (ADC) and Gleason score and prostate specific antigen (PSA) in prostate cancer.Methods:We retrospectively analyzed the diffusion weighted imaging (DWI) and ADC value of 53 patients with benign prostatic hyperplasia (28 cases) and prostate cancer (25 cases) admitted in our hospital from April 2013 to March 2016,and further analyzed the relationship between ADC and Gleason score and serum total-PSA (t-PSA) content.Results:The ADC value of prostatic hyperplasia was (1.21±0.12) × 10 3 mm2/s,the ADC value of prostate cancer was(0.69±0.09) × 10-3 mm2/s,and the difference was statistically significant (t =27.932,P =0.004).The diagnostic specificity was 92.8％ and the sensitivity was 96.0％ with the cut-off ADC value of 0.969 × 10-3 mm2/s.The ADC value was negatively correlated to Gleason score (r=-0.581,P=0.021),and t-PSA (r=-0.339,P=0.023).Conclusion:DWI correlated with ADC value in the 1.5 T magnetic field was valuable for the diagnosis of prostate cancer,and ADC value could indicate the degree of tumor differentiation.关键词
前列腺癌/扩散加权成像/Gleason评分/肿瘤标志物Key words
prostate cancer/diffusion weighted imaging/Gleason score/tumor markers分类
医药卫生引用本文复制引用
张勇..1.5 T MR扩散加权成像对前列腺癌诊断价值及其ADC值与Gleason评分、肿瘤标志物的相关性分析[J].广西医科大学学报,2017,34(7):1037-1040,4.
