广西医学2017,Vol.39Issue(4):477-480,4.DOI:10.11675/j.issn.0253-4304.2017.04.14
颈动脉分叉部解剖结构对颈动脉血流动力学的影响及其与颈动脉粥样硬化斑块形成的关系
Influence of anatomical structure of carotid bifurcation on carotid hemodynamics and its relationship with formation of carotid atherosclerotic plaque
摘要
Abstract
Objective To investigate the influence of anatomical structure of carotid bifurcation on the hemodynamics and its relationship with the formation of carotid atherosclerotic plaque.Methods A total of 86 patients (172 sides) with suspected carotid atherosclerosis were detected for the vascular morphology and lumen structure from the distal segment of carotid artery(CCA) to the initial part of internal carotid artery (ICA) to learn the anatomical structure of carotid bifurcation and atherosclerotic plaque formation.Peak systolic velocity (PSV),end diastolic velocity(EDV) and resistance index(RI) in CCA and ICA,and HR,mean arterial pressure (MAP),central venous pressure (CVP),cardiac index(CI) and pulmonary capillary wedge pressure (PCWP) were determined and compared among different types of carotid bifurcation.Results Among 86 patients (172 sides),there were 96 sides with carotid artery bifurcations of the straight and curved type (55.81%),58 of the curved type(33.72%) and 18 of the straight type(10.47%),and the proportion of the straight and curved type were higher than those of another two types (P < 0.05).There were no significant differences in PSV,EDV or RI among three different types of carotid bifurcation in the CCA and ICA(P > 0.05),but the PSVICA/PSVCCA ratios of the straight and curved type and the curved type were significant higher than that of the straight type (P < 0.05).No significant difference was observed in the HR,MAP,CVP or PCWP among different types of carotid bifurcation(P > 0.05),but CI of the curved type was significantly lower than that of the straight type (P < 0.05).The straight and curved type had significantly higher incidencc rate of atherosclerotic plaque compared to the straight and curved type and the curved type (P < 0.05).Conclusion The anatomical structure of carotid artery bifurcation might have an impact on the blood flow velocity and dynamic parameters of carotid artery,and it's closely related to the formation of atherosclerotic plaque.关键词
颈动脉分叉部解剖结构/血流动力学/颈动脉粥样硬化斑块Key words
Anatomical structure of carotid bifurcation/Hemodynamics/Carotid atherosclerotic plaque分类
医药卫生引用本文复制引用
谭庆晶,古联,王天保,季兴,张德敏,江志滨..颈动脉分叉部解剖结构对颈动脉血流动力学的影响及其与颈动脉粥样硬化斑块形成的关系[J].广西医学,2017,39(4):477-480,4.基金项目
广西医药卫生科研课题(Z2015302) (Z2015302)