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妊娠妇女血清亮氨酸氨基肽酶的水平变化及其临床意义

胡晓英 柳洲 吴建发 舒志明 孙贻娟 冯云 杨辰敏

广西医学2017,Vol.39Issue(7):961-963,3.
广西医学2017,Vol.39Issue(7):961-963,3.DOI:10.11675/j.issn.0253-4304.2017.07.09

妊娠妇女血清亮氨酸氨基肽酶的水平变化及其临床意义

Variation of serum leucine aminopeptidase level and its clinical significance in pregnant women

胡晓英 1柳洲 1吴建发 1舒志明 1孙贻娟 2冯云 2杨辰敏2

作者信息

  • 1. 上海市浦东新区周浦医院妇产科,上海市 201318
  • 2. 上海交通大学医学院附属瑞金医院妇产科,上海市 200025
  • 折叠

摘要

Abstract

Objective To explore the variation of serum leucine aminopeptidase(LAP) level and its clinical significance in pregnant women.Methods A total of 120 normal pregnant women with normal delivery were enrolled as normal pregnant group,and were divided into early-term normal group,mid-term normal group and late-term normal group according to the gestational week,with 40 cases in each subgroup.Twenty-eight women with gestational hypertension,26 women with premature labor and 30 healthy non-pregnant women were enrolled as gestational hypertension group,preterm group and non-pregnant group respectively.The serum LAP level was detected in each group.Results The serum LAP level increased in the order of non-pregnant group,preterm group,normal pregnant group and gestational hypertension group(P<0.05).The serum LAP level decreased in the order of late-term normal group,mid-term normal group and early-term normal group(P<0.05).The serum LAP level positively correlated with the gestational week in the normal pregnant women(P<0.05).Conclusion The variation of serum LAP level presents a certain rule in the pregnant women.Monitoring LAP level is significantly valuable for the evaluation of gestational hypertensive disease and premature labor.

关键词

妊娠/亮氨酸氨基肽酶/血清/妊娠期高血压/早产

Key words

Pregnancy/Leucine aminopeptidase/Serum/Gestational hypertension/Premature labor

分类

医药卫生

引用本文复制引用

胡晓英,柳洲,吴建发,舒志明,孙贻娟,冯云,杨辰敏..妊娠妇女血清亮氨酸氨基肽酶的水平变化及其临床意义[J].广西医学,2017,39(7):961-963,3.

基金项目

上海市教育委员会曙光跟踪项目(10GG10) (10GG10)

上海市重点学科建设项目(S30201) (S30201)

上海市科学技术委员会科研项目(12XD1406500) (12XD1406500)

广西医学

OACSTPCD

0253-4304

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