解放军医药杂志2017，Vol.29Issue(4)：95-98,4.DOI:10.3969/j.issn.2095-140X.2017.04.025
不同妊娠次数O型血孕妇新生儿ABO溶血病发生情况及其与体内抗体效价的相关性研究
A Study on Incidence of ABO Haemorrhagic Disease of Newborn Gaving Birth by O-type Blood Puerpera Women with Different Gravidities and Its Relationship with Antibody Titer in Vivo
摘要
Abstract
Objective To investigate incidence of ABO-hemolytic disease of newborn (ABO-HDN) giving birth by O-type blood puerperal women with different gravidities and its correlation with antibody titer in vivo.Methods A total of 86 O-type blood women with primigravida (group A),48 O-type blood women with two times of pregnancies (group B) and 58 O-type blood women with more than 2 times of pregnancies (group C) during January 2013 and May 2016 were recruited in this study.Incidence of ABO-HDN was observed,and serum IgG antibody titer detection was also performed,and the relationship between incidence of ABO-HDN in O-type blood puerperal women with different gravidities and its antibody titers in vivo was analyzed.Results The total positive rates of IgG anti-A (B) antibody titer in group B and C were significantly higher than that in group A,and the rate in group C was significant higher than that in group B (P ＜ 0.05).Incidence rate of ABO-HDN was increased with the increasing IgG anti-A (B) antibody titer (P ＜ 0.05).Gravidity was positively related to IgG anti-A (B) antibody titer and ABO-HDN morbidity (P ＜ 0.05).Conclusion Prenatal serum IgG anti-A (B) antibody titer detection can reduce or avoid the incidence of ABO-HDN for O-type blood puerperal women.关键词
幼红细胞增多症,胎儿/妊娠次数/抗体效价Key words
Erythroblastosis, fetal/Gravidity/Antibody titer分类
医药卫生引用本文复制引用
马经琼,谢孝森..不同妊娠次数O型血孕妇新生儿ABO溶血病发生情况及其与体内抗体效价的相关性研究[J].解放军医药杂志,2017,29(4):95-98,4.基金项目
湖北省卫生厅青年人才基金资助项目(QJX2012-47) （QJX2012-47）
