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原发性高血压患者胰岛素抵抗与抗心磷脂抗体的分析

伍晓梅 朱玲 吴琳娜

河北医学2017,Vol.23Issue(7):1064-1067,4.
河北医学2017,Vol.23Issue(7):1064-1067,4.DOI:10.3969/j.issn.1006-6233.2017.07.003

原发性高血压患者胰岛素抵抗与抗心磷脂抗体的分析

Analysis of Insulin Resistance and Anticardiolipin Antibodies in Patients with Essential Hypertension

伍晓梅 1朱玲 1吴琳娜1

作者信息

  • 1. 四川大学华西医院健康管理中心, 四川 成都 610000
  • 折叠

摘要

Abstract

Objective:To explore the association of insulin resistance and anticardiolipin antibodies in patients with essential hypertension.Methods: 120 patients with essential hypertension in our hospital from February 2015 to February 2016 were selected as experimental group.56 healthy subjects were selected at the same time in our hospital as the control group.The body mass index, fasting insulin and fasting blood glucose were compared between the two groups.Insulin resistance indexes were calculated in two groups.Anticardiolipin antibodies (ACA-IgG, ACA-IgM) levels of the two groups were compared.Assosiations between insulin resistance and ACA-IgG and ACA-IgM were analyzed.Results: The fasting insulin level and insulin resistance index in the experimental group were significantly higher than those in the control group (P<0.05).The serum ACA-IgG and ACA-IgM in the experimental group were significantly higher than those in the control group (P<0.05).Serum ACA-IgG level was positively correlated with insulin resistance (P<0.05), but there was no correlation between serum ACA-IgM level and insulin resistance (P>0.05).Conclusion: There''s significant insulin resistance in patients with essential hypertension, and there''s a positive correlation between the level of serum ACA-IgG and the level of resistance.It suggests that there is a tendency to thrombosis in patients with essential hypertension.

关键词

原发性高血压/胰岛素抵抗/抗心磷脂抗体

Key words

Essential hypertension/Insulin resistance/Anticardiolipin antibody

引用本文复制引用

伍晓梅,朱玲,吴琳娜..原发性高血压患者胰岛素抵抗与抗心磷脂抗体的分析[J].河北医学,2017,23(7):1064-1067,4.

基金项目

四川省科技厅资助项目,(编号:2014023651) (编号:2014023651)

河北医学

OACSTPCD

1006-6233

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