华南农业大学学报2017，Vol.38Issue(4)：76-79,4.DOI:10.7671/j.issn.1001-411X.2017.04.013
3种高致病性猪蓝耳病疫苗对仔猪免疫器官的损伤作用
Injury to immune organs of piglets from three kinds of PRRS vaccine
摘要
Abstract
[Objective] To study the injury to immune organs of piglets from three kinds of PRRS vaccine(MLV, TJM 92 and JXA-1R vaccines).[Method]Fifty new-born healthy piglets were devided into four groups:non-immunized control group(CK group), MLV vaccine group(A group), TJM 92 vaccine group (B group), JXA-1R vaccine group (C group).Every piglit in the experimental group were vaccinated.Then paraffin sections were prepared after pathological anatomy.Changes in percentages of esterase-positive T cells and plasma cells (effector B cells) of different immune organs were summarized by using optimized esterase (α-NAE) and methyl green-pyronin (MG-P) staining.[Result]There were significant or highly significant differences in the percentages of esterase-positive T cells and plasma cells of immune organs between each immunized group and CK group.[Conclusion]Three kinds of vaccine all have injuries to immune organs of piglets.Injury from JXA-1R vaccine is the strongest, followed by TJM92 vaccine and then MLV vaccine.关键词
猪蓝耳病/疫苗/损伤/酯酶染色/甲基绿-派洛宁染色/仔猪/免疫器官Key words
porcine reproductive and respiratory syndrome/vaccine/injury/esterase staining/methyl green-pyronin staining/piglet/immune organ分类
农业科技引用本文复制引用
罗六龙,马春全,梁梓森..3种高致病性猪蓝耳病疫苗对仔猪免疫器官的损伤作用[J].华南农业大学学报,2017,38(4):76-79,4.基金项目
广东高校畜禽疾病诊断防控技术开发中心资助项目(GCZX-B1102) （GCZX-B1102）
