中国实用神经疾病杂志2017，Vol.20Issue(12)：1-4,4.
全面性发作癫痫患者的情绪词汇加工
Processing of emotional words in patients with generalized seizures
摘要
Abstract
Objective To evaluate whether epilepsy patients are complicated with cognitive impairment and emotional disorders or not by comparing the processing of different emotional words in patients with generalized seizures.Methods Event-related potential (ERP) technique was used to record the differences of emotional reactions stimulated by the three different emotional words in patients with generalized seizures and in controls.Results Compared with control group,the epilepsy group showed significant differences in Hamilton depression scale scores,accuracy rate and average reaction time (all P<0.05) and showed longer reaction time after the stimulus of negative emotional words.Statistical parameters presented by T-test displayed that ERPs in bilateral posterior temporal regions and occipital pole showed significant differences between two groups after 130-160ms stimulus of three different emotional words (P<0.05);The two groups indicated significant differences at the stage of attention processing after 400-600ms negative emotional stimulus and at the stage of further processing after positive emotional stimulus (P<0.05);In addition,ERPs in frontal pole and front frontal region showed significant differences between two groups after 310-950ms neutral stimulus (P<0.05).Conclusion Patients with generalized seizures have high occurrence rate of emotional disorders such as depression,and the stimulus of emotional words can decrease efficiency,prolong reaction time and increase accuracy rate.关键词
全面性发作癫痫/事件相关电位/认知障碍/情绪障碍/情绪加工Key words
Generalized seizure/Event-related potential/Cognitive impairment/Emotional disorders/Emotion processing分类
医药卫生引用本文复制引用
何良玉,陈湛愔,陈瑞珍,许雯蔚,高俊杰,何国林,李达枢..全面性发作癫痫患者的情绪词汇加工[J].中国实用神经疾病杂志,2017,20(12):1-4,4.基金项目
广东省科技厅社会发展基金(2011B031800397) （2011B031800397）
