核农学报2017，Vol.31Issue(8)：1509-1514,6.DOI:10.11869/j.issn.100-8551.2017.08.1509
雅安藏茶茶多糖对60Co-γ射线辐照损伤小鼠抗氧化和造血功能的防护作用
Protective Effects of Ya'an Tibetan Tea Polysaccharide on Mice Antioxidant Function and the Hematopoietic System induced by 60Co-γ Ray Radiation
摘要
Abstract
In order to investigate the effect of tea polysaccharide on the radiation resistance of 60Co-γ ray radiation injury mice,tea polysaccharide extracted from Ya'an Tibetan tea was used as material,Mice were treated with different concentrations of tea polysaccharide for 15 days.On day 6,5Gy60Co-γ ray was used to irradiate mice in each group,The total antioxidant capacity (T-AOC),total superoxide dismutase (T-SOD) activity and total protein (TP) content in the peripheral blood cells and liver tissues of each group were measured on the 16th day after intragastric administration.The results showed that compared with the radiation group alone,the tea polysaccharides in Ya'an can significantly increase the number of peripheral blood cells in radiation-injured mice,the liver tissue T-AOC,T-SOD activity was significantly increased,the liver MDA content was significantly reduced,the femoral bone marrow DNA content was significantly increased and relieves the immune organ thymus atrophy,And with the increase of tea polysaccharide concentration,its anti-radiation effect is enhanced.In conclusion,the tea polysaccharides in Ya'an had a strong protective effect on the anti-oxidative function and hematopoietic function of mice irradiated by 60Co-γ ray radiation,and had a certain dose effect.The results of this study provide a new reference for further study on the mechanism of polysaccharide radiation,and also provide a theoretical basis for the study of radiation health care in Ya'an Tibetan tea.关键词
雅安藏茶/茶多糖/60Co-γ射线辐照/抗氧化/造血功能Key words
Ya'an Tibetan tea/tea polysaccharide/60Co-γ ray radiation/antioxidant fuction/hematopoietic function引用本文复制引用
李解,吴家乐,谭晓琴,林莉岚,郭承义,许靖逸,何春雷..雅安藏茶茶多糖对60Co-γ射线辐照损伤小鼠抗氧化和造血功能的防护作用[J].核农学报,2017,31(8):1509-1514,6.基金项目
雅安市市校合作项目,雅安藏茶保健功能研究及成果应用示范推广 （）
