实用临床医药杂志2017，Vol.21Issue(13)：29-31,3.DOI:10.7619/jcmp.201713008
化疗对晚期肺癌患者肿瘤标志物水平变化的影响
Influence of chemotherapy on the changes of tumor markers levels in patients with advanced lung cancer
陈天明 1余国辉 1李任翔 1卢青2
作者信息
- 1. 湖北省荆门市第一人民医院 呼吸内科,湖北 荆门,448000
- 2. 荆楚理工学院医学院 呼吸内科,湖北 荆门,448000
- 折叠
摘要
Abstract
Objective To observe the influence of chemotherapy on the changes of tumor markers levels in patients with advanced lung cancer.Methods A total of 75 patients with advanced lung cancer were selected amd treated with the combination of two drugs based on platinum.The therapeutic effect was judged by the changes of solid tumor according to medical image.The levels of tumor markers before and after the treatment were tested by chemiluminescence immunoassay,and tumor markers including cancer embryonic antigen(CEA),neuron specific enolase(NSE),carbohydrate antigen 125(CA125),cytokeratin(CYFRA211),squamous cell cancer antigen(SCC).Results The levels of tumor markers were significantly lower after the treatment than those before the treatment(P<0.05).The decreased level of patients with CR and PR were significantly lower than those with SD and PD(P<0.05).There was significant difference in the changes of tumor markers levels before and after treatment between the patients with different tumor types.Conclusion Effective chemotherapy can significantly decrease the levels of tumor markers in patients with advanced lung cancer.关键词
化疗/晚期肺癌患者/肿瘤标志物水平Key words
chemotherapy/patients with advanced lung cancer/levels of tumor markers分类
医药卫生引用本文复制引用
陈天明,余国辉,李任翔,卢青..化疗对晚期肺癌患者肿瘤标志物水平变化的影响[J].实用临床医药杂志,2017,21(13):29-31,3.
