临床神经病学杂志2017，Vol.30Issue(3)：166-170,5.
偏头痛脑白质高信号与临床特征及右向左分流的相关分析
Association analysis of the white matter hyperintensities and clinical characteristics and right-to-left shunt in migraine
摘要
Abstract
Objective To explore the risk factors of white matter hyperintensities (WMHs) in migraine patients from the perspectives of clinical characteristics and to investigate whether right-to-left shunt (RLS) relates to the WMHs.Methods Migraine patients were recruited to complete a questionnaire involving headache features, and underwent contrast-enhanced TCD for detecting the presence and grade of RLS and brain MRI scanning for WMHs evaluation.Results Fifty-seven migraine patients were enrolled.WMHs were detected in 18 cases(31.6%).The WMHs were mainly located in the frontal and parietal lobe and the lesions were generally mild.The differences of age, gender, headache features, scores of anxiety and depression and RLS between WMHs group and non-WMHs group were compared, and only age (P=0.002) and disease duration (P=0.046) showed significant differences.Conclusions WMHs in migraine are mainly located in frontal and parietal lobe.Age and disease duration may be the risk factors of the WMHs.The associations between the presence of WMHs and the presence of aura, attack frequency, headache duration, headache degree or anxiety and depression are not found.RLS is neither associated with the risk of WMHs in migraine.关键词
偏头痛/脑白质高信号/右向左分流Key words
migraine/white matter hyperintensities/right-to-left shunt分类
医药卫生引用本文复制引用
谢惠,罗国刚,张强,荐志洁,卞益同,霍康,刘蕊,朱丹,张丽辉,杨健..偏头痛脑白质高信号与临床特征及右向左分流的相关分析[J].临床神经病学杂志,2017,30(3):166-170,5.基金项目
国家十二五科技支撑计划(2014BAI04B05) （2014BAI04B05）
