临床神经病学杂志2017，Vol.30Issue(3)：175-178,4.
颈动脉内膜剥脱术前他汀应用对患者转归影响的观察性研究
Effect on the outcomes with statins pre-treatment before carotid endarterectomy in patients with atherosclerotic carotid stenosis
摘要
Abstract
Objective To oberve the effect on outcomes of patients with atherosclerotic carotid stenosis with long-term statins pre-treatment (LST) or peri-procedure statins (PST) treatment before carotid endarterectomy (CEA).Methods The clinical data about 31 patients with carotid stenosis who received CEA were collected, of which 15 cases in LST group, another 16 cases in PST group.The clinical data of these two groups were observed as the status of restenosis, death and stroke reoccurrence were compared parallelly.Results Both groups did not differ each other in baseline data, while the level low density lipoprotein cholesterin in LST was lower significantly than that in PST group (P<0.05).No statistical difference was found between two groups in preoperative symptoms and degree of stenosis.Both groups had no stroke reoccurrence.In PST group, there were one death case and one restenosis case, while there was none of death and restenosis in LST group.Therefore, there was no statistic difference in the restenosis and death between two groups.Conclusion There is no remarked difference on the outcome for CEA patients between PST group and LST group, which suggested that peri-procedural statin treatment is of significance for CEA patients.关键词
他汀/颈动脉内膜剥脱术/转归Key words
statin/carotid endarterectomy/outcome分类
医药卫生引用本文复制引用
刘慧慧,黄亚波,张艳林,尤寿江,曹勇军,刘春风..颈动脉内膜剥脱术前他汀应用对患者转归影响的观察性研究[J].临床神经病学杂志,2017,30(3):175-178,4.基金项目
国家自然科学青年基金(81200894) （81200894）
国家自然科学基金面上项目(81471195) （81471195）
江苏省自然科学基金(BK20122172) （BK20122172）
