临床神经病学杂志2017，Vol.30Issue(3)：221-223,3.
婴儿型脊肌萎缩症的神经电生理特点
Diagnostic value of electrophysiological examinations in infantile spinal muscular atrophy
吴雪燕 1李红勤1
作者信息
- 1. 214000 无锡市人民医院神经电生理室
- 折叠
摘要
Abstract
Objective To explore electrophysiological features of infantile spinal muscular atrophy (SMA), and to evaluate diagnostic value of electrophysiological examinations in patients with SMA.Methods Tweenty-seven SMA children from Jan 2011 to Nov 2015 diagnosed in Wuxi People''s Hospital were enralled.All patients had neurogenic changes by EMG and finally confirmed by genetic test as SMA.Basic clinical data were retrospectively analyzed.Nerve conduction velocity was tested in each patient;While EMG was performed in no less than six muscles in each patient.Results All these patients were characterized by progressive flaccid paralysis in limbs.In all cases, amplitude of CMAP in median nerve was significantly decreased, apparent decreased in ulnar nerve and peroneal nerve;while mild decrease of MCV was appeared in ulnar nerve.Nothing abnormal were detected in sensory nerve conduction.EMG demonstrated neurogenic damage.Conclusion Typical clinical symptoms of infantile SMA are progressive symmetrical loss of muscle control and atrophy in limbs, and specificity electrophysiological representation provides very important basis for the diagnosis.关键词
婴儿型脊肌萎缩症/EMG/神经运动传导Key words
infantile spinal muscular atrophy/EMG/motor nerve conduction分类
医药卫生引用本文复制引用
吴雪燕,李红勤..婴儿型脊肌萎缩症的神经电生理特点[J].临床神经病学杂志,2017,30(3):221-223,3.
