临床误诊误治2017，Vol.30Issue(7)：6-10,5.DOI:10.3969/j.issn.1002-3429.2017.07.002
垂体转移癌四例误诊分析并文献复习
Pituitary Metastatic Carcinoma: Analysis of Four Misdiagnosed Cases and a Literature Review
摘要
Abstract
Objective To analyze clinical features and misdiagnosed causes of pituitary metastatic carcinoma so as to improve the diagnosis and treatment for pituitary metastatic carcinoma.Methods Clinical data of 4 misdiagnosed patients with pituitary metastatic carcinoma admitted during August 2010 to August 2013 was retrospectively analyzed, and related literature was also reviewed.Results The main symptom of the 4 patients was hypopsia, there were 2 patients associated by diabetes insipidus, 2 patients associated by headache and 1 patient associated by ocular motility disorders, and all patients had different degrees of hypopituitarism.Preoperative iconography examination for the 4 patients showed that occupying lesions in saddle area, but the 4 patients were misdiagnosed as having craniopharyngioma, pituitary adenoma, tuberculum sellae meningioma and chordoma respectively.Tumor resection was performed for all patients, and metastatic adenocarcinoma was confirmed by postoperative pathological examination.Primary lesions of two patients came from the lung, and one came from mammary gland, but another patient did not find source because of the economy.Conclusion Pituitary metastatic carcinoma is a rare lesion in intracalvarium, and most lesions come from mammary gland and lungs.Primary manifestations mainly are optic nerve lesion, diabetes insipidus, hypopituitarism and extraocular palsy.The differential diagnosis of pituitary metastatic carcinoma with other tumors in saddle area is difficult, and confirmed diagnosis should be performed pathological examination.关键词
垂体肿瘤/肿瘤转移/误诊/颅咽管瘤/垂体腺瘤/鞍结节脑膜瘤/脊索瘤Key words
Pituitary neoplasms/Neoplasm metastasis/Misdiagnosis/Craniopharyngioma/Pituitary adenoma/Tuberculum sellae meningioma/Chordoma分类
医药卫生引用本文复制引用
杨宝,朱海波,张霓嘉,姜涛,王集生,贾旺,贾桂军,王硕..垂体转移癌四例误诊分析并文献复习[J].临床误诊误治,2017,30(7):6-10,5.基金项目
国家科技支撑计划项目(2013BAI09B03) （2013BAI09B03）
