环境与职业医学2017，Vol.34Issue(6)：503-510,8.DOI:10.13213/j.cnki.jeom.2017.16633
倒班年限与男性钢铁工人2型糖尿病患病率的剂量-反应关系
Dose-response relationship between shift work years and diabetes mellitus type 2 in male steel workers
摘要
Abstract
[Objective] To assess the dose-response relationship between male steel workers' shift work years and prevalence of diabetes mellitus type 2 (T2DM).[Methods] A total of 7415 male steel workers were enrolled to occupational health examination and health examination from February 2015 to February 2016 in a hospital of steel company,and 7 209 questionnaires were included in the current crosssectional analysis.Data were collected on demographic characteristics,lifestyle,medical history,family history,height,weight,and occupational history of the participants.Multiple non-conditional logistic regression model and restricted cubic spline model were used to assess the relationship between shift work years and prevalence of T2DM in the selected male steel workers.[Results] The prevalence rate of T2DM was 16.5％ in the participants.Previous shift work (OR=1.403,95％CI:1.131-1.740) and current shift work (OR=1.536,95％CI:1.298-1.817) were associated with T2DM (P＜0.05).After adjusting for general factors and occupational factors such as high temperature exposure,the above two factors were still associated with the prevalence rate of T2DM (P ＜ 0.05),with ORs (95％CI) being 2.792 (2.286-3.41 1) and 2.546 (2.076-3.124),respectively.There was a significant correlation (x2=35.00,P＜ 0.000 1) and a nonlinear correlation (x2=3.00,P=0.606 8) between previous shift work years and T2DM.There was also a significant correlation (x2=49.92,P ＜ 0.000 1) and a nonlinear correlation (x2=5.33,P=0.148 9) between current shift work years and T2DM.[Conclusion] Shift work years are associated to the prevalence of T2DM in a nonlinear pattern in male steel workers.关键词
男性钢铁工人/倒班年限/2型糖尿病/限制性立方样条模型Key words
steel worker/shift work duration/diabetes mellitus type 2/restricted cubic spline model分类
医药卫生引用本文复制引用
车崇亮,李小明,马石头,范红敏,肖孟迎,王朝阳,高雪娟,陆瑶,丛龙学,袁聚祥,胡泊..倒班年限与男性钢铁工人2型糖尿病患病率的剂量-反应关系[J].环境与职业医学,2017,34(6):503-510,8.基金项目
河北省科技支撑重大项目(编号:132777090) （编号:132777090）
河北省自然科学基金课题(编号:H2016209058) （编号:H2016209058）
国家重点研发计划:精准医学研究(编号:2016YFC0900605) （编号:2016YFC0900605）
