肿瘤预防与治疗2017，Vol.30Issue(3)：168-173,6.DOI:10.3969/j.issn.1674-0904.2017.03.004
宫颈癌根治术后并发无症状盆腔淋巴囊肿调强放疗的临床研究
Clinical Study of Intensity-modulated Radiotherapy to Treat Asymptomatic Pelvic Lymphocyst after Radical Operation for Cervical Cancer
摘要
Abstract
Objective: To explore the feasibility of intensity-modulated radiotherapy (IMRT) to treat the asymptomatic pelvic lymphocyst(PL) appeared after radical operation for cervical cancer.Methods: From January 2015 to February 2016,92 cervical cancer patients who had the post operative indications of radiotherapy were enrolled in this study.Patients were divided into the experimental group (PL were detected and with the diameter less than or equal to 6cm,46 cases) and the control group (PL were not detected,46 cases) according to whether asymptomatic PL were detected by the simulation computed tomography (CT).PL were all included in the clinical target volume (CTV) of the experimental group,and the same technology of IMRT treatment plans were applied in these two groups.The influence of PL on IMRT was analyzed by means of dose volume histogram (DVH) and the acute radiation reaction of organ at risk (OAR) such as acute radiation enteritis,cystitis and proctitis.In addition,the outcome of PL was observed at the end of radiotherapy and 3 months after radiotherapy.Results: The volume of CTV in the experimental group was significantly larger than that in the control group (P<0.05).The irradiation dose volume for small intestine,rectum and bladder of the two groups were of no significant difference(P>0.05).Also no significant difference was observed of the incidence of acute radiation reaction of small intestine,rectum,bladder between these two groups (P>0.05).The curative efficacy of PL in the experimental group was 60.61% at the end of radiotherapy and 89.32% 3 months after radiotherapy.Conclusion: For the asymptomatic PL appeared after radical operation for cervical cancer patients,timely IMRT treatment is effective without the increasing of acute radiation reaction of small intestine,rectum,and bladder.关键词
盆腔淋巴囊肿/调强放疗/宫颈癌Key words
Pelvic Lymphocyst/Intensity-modulated Radiotherapy/Cervical Cancer分类
医药卫生引用本文复制引用
于娇,刘国强,高晖,曹席明,雷雨..宫颈癌根治术后并发无症状盆腔淋巴囊肿调强放疗的临床研究[J].肿瘤预防与治疗,2017,30(3):168-173,6.基金项目
陕西省社会发展科技攻关项目(编号:2016SF-265) （编号:2016SF-265）
