山东农业科学2017，Vol.49Issue(7)：167-172,6.DOI:10.14083/j.issn.1001-4942.2017.07.035
生长分化因子9在哺乳动物生殖中的作用
Roles of Growth Differentiation Factor 9 (GDF9) in Mammalian Reproduction
摘要
Abstract
Growth differentiation factor 9 (GDF9) is essential for the regulation of mammalian reproduction.As a member of transforming growth factor beta (TGFβ) family, GDF9 is mainly expressed in ovarian oocytes.In addition to the classical GDF9/Smads signal transduction pathway to implement biological response, GDF9 can also achieve its physiological role by independent of Smads.GDF9 plays important roles in follicle and oocyte development, ovulation, corpus luteum formation, spermatogenesis, fertilization, embryo development and so on.In this paper, the gene expression, protein structure, signaling pathway of GDF9 and its possible biological functions in the process of mammalian reproduction were summarized and discussed.关键词
生长分化因子9/哺乳动物/生殖Key words
Growth differentiation factor 9/Mammal/Reproduction分类
农业科技引用本文复制引用
王建英,刘昭华,曹顶国,王金文,崔绪奎,张果平..生长分化因子9在哺乳动物生殖中的作用[J].山东农业科学,2017,49(7):167-172,6.基金项目
山东省农业科学院农业科技创新工程项目"畜禽种质资源保护与共享利用"(CXGC2016A04) （CXGC2016A04）
国家现代农业产业技术体系肉羊产业技术体系项目"圈舍设计与环境控制"(CARS-39) （CARS-39）
公益性行业(农业)科研专项"奶山羊产业技术研究与试验示范"(201103038) （农业）
山东省星火计划项目"良种肉羊高效繁育体系技术集成与示范"(2013GXH21010) （2013GXH21010）
