山东医药2017，Vol.57Issue(27)：9-13,5.DOI:10.3969/j.issn.1002-266X.2017.27.003
516例缺血性小卒中患者SSS-TOAST分型结果及颅内梗死灶分析
SSS-TOAST classification and cerebral infarction lesions in 516 ischemic minor stroke patients
摘要
Abstract
Objective To observe the SSS-TOAST classification and to analyze the characteristics of cerebral infarction lesions in 516 patients with ischemic minor stroke.Methods The SSS-TOAST classification and lesions analysis were performed in 516 patients with ischemic minor stroke.The data including age,Essen stroke risk scale (ESRS) score,90 d modified Rankin scale (mRS) score,head magnetic resonance imaging (MRI) + magnetic resonance angiography (MRA) + diffusion-weighted imaging (DWI),and cervical vascular examination,etc.were collected.Then we did comparisons between the different SSS-TOAST sub-types.Results The SSS-TOAST classification showed that: there were 174 (33.72%) patients with large-artery atherosclerosis subtype,39 (7.56%) patients with cardioembolism subtype,229 (44.38%) patients with small-artery occlusion subtype,11 (2.13%) patients with other determined etiology subtype,and 63 (12.21%) patients with undetermined cause subtype.The main subtypes were small-artery occlusion and large-artery atherosclerosis.We compared these two subtypes and found that patients with large artery atherosclerosis subtype had more arteriostenosis and bad outcomes at 90 d mRS (all P<0.05).Totally 357 (69.19%) patients had isolated lesions,and the isolated lesions of 231 (64.71%) cases occurred mainly in subcortical location,deep white matter,and basal ganglia;159 (30.81%) patients had multiple lesions.The diameter (or sum) of lesion in 282 (54.65%) patients was less than 20 mm,and 234 (45.35%) patients'' lesion diameter (or sum) was ≥20 mm.These cerebral infarction lesions in patients with ischemic minor stroke were mostly isolated,diameter< 20 mm,and the isolated lesions were mostly found in common locations (all P<0.05).Conclusions The main SSS-TOAST subtypes are large-artery atherosclerosis and small-artery occlusion in patients with ischemic minor stroke,the ratios of arteriostenosis and bad outcomes mainly occur in patients with large-artery atherosclerosis subtype.These cerebral infarction lesions are mostly isolated and found in common locations.However,some patients have infarction diameter≥20 mm and multiple infarction.关键词
脑梗死/缺血性小卒中/大动脉粥样硬化/小动脉闭塞Key words
cerebral infarction/ischemic minor stroke/large-artery atherosclerosis/small artery occlusion分类
医药卫生引用本文复制引用
游文霞,钟剑萍,欧阳基鹏,黎宏庄,杨少民,胡秋根..516例缺血性小卒中患者SSS-TOAST分型结果及颅内梗死灶分析[J].山东医药,2017,57(27):9-13,5.基金项目
佛山市医学类科技攻关项目(2014AB001533). （2014AB001533）
