摘要
Abstract
Objective To investigate the relationship between thyroid hormones and nutritional status in elderly patients.Methods Total 840 patients aged above 60 years admitted in hospital, including 385 males and 455 females were enrolled in the study.Anthropometric indexes, serum FT3, FT4, TSH levels and nutritional biochemical parameters were measured, and the association of TSH levels with lipid profiles and nutritional indices was analyzed.Results In this group of elderly patients, the prevalence of subclinical hypothyroidism (SCH) and subclinical hyperthyroidism was 4.5% and 2.3%, respectively.Lipid profiles, serum TSH level were higher in women than those in men.In women, the levels of serum TC and Apo B were higher in SCH than those in euthyroidism ( t =-2.288, P =0.023; t =-1.995, P =0.047);while in men, BMI and AC were significantly lower in patients with SCH than those in euthyroidism ( t =2.152, P =0.032; t =2.233, P =0.026).The partial correlation analysis revealed that serum TSH levels was positively correlated with serum TC and serum Alb in women ( r =0.097, P =0.045; r =0.118, P =0.015).Serum TSH was negatively correlated with BMI and AC ( r =-0.122, P =0.020; r =-0.122, P =0.020), and positively correlated with serum TG ( r =0.107, P =0.107) in men.The prevalence of hypertension, prior myocardial infarction, atrial fibrillation and coronary heart disease was not associated with SCH ( P >0.05).Conclusion Subclinical hypothyroidism is associated with hypercholesterolemia and nutritional status in elderly inpatients;however, elderly patients with SCH are unlikely to increase the risk of cardiovascular diseases.关键词
老年人/亚临床甲状腺功能减退/血脂/体质量指数/上臂围Key words
elderly/subclinical hypothyroidism/lipid profile/body mass index/arm circumference分类
医药卫生
