同济大学学报（医学版）2017，Vol.38Issue(3)：115-119,5.DOI:10.16118/j.1008-0392.2017.03.024
上海市大气颗粒污染物对居民出血性脑卒中住院人数的影响
Association between ambient PM levels and daily hemorrhagicstroke inpatients in Shanghai
摘要
Abstract
Objective To explore the effects of ambient particulate matter(PM)level on daily hemorrhagic stroke inpatients in shanghai.Methods The daily air pollution and meteorological factors between January 2013 and December 2014 in Shanghai were continuously monitored;and the data of daily hemorrhagic stroke inpatients in the corresponding period were collected.Poisson regression model incorporating natural spline smooth functions (generalized linear models, GLM) were applied to adjust for long-term, seasonal trends and weekend effect, public holiday and other confounding factors.ResultsSingle hysteresis showed that the effect of PM2.5 and PM10 on hemorrhagic stroke inpatients was the strongest on the day of the event.In the single pollution model, for a 10μg/m3 increase of the ambient PM2.5 and PM10 concentration, the corresponding increase of hemorrhagic stroke inpatients was 0.36% (95% CI: 0.27%-0.44%)and 0.49%(95% CI: 0.42%-0.55%).The cumulative hysteresis showed that effect of PM on hemorrhagic stroke inpatients was the strongest on the third day of lagging (lag 03), for a 10μg/m3 increase of the ambient PM2.5 and PM10 concentration, the corresponding increase of hemorrhagic stroke inpatients was 0.29%(95% CI: 0.16%-0.41%)and 0.46%(95% CI: 0.37%-0.56%), respectively.Stratified analysis showed that the PM effect was more significant in females and people aged 66-85 years.When the PM2.5 concentration was increased by 10μg/m3, the number of inpatients increased by 0.39% (95% CI: 0.28%-0.49%) and 0.37% (95% CI: 0.41%-0.59%);when the concentration of PM10 was increased by 10μg/m3, the number of outpatients increased by 0.50%(95% CI: 0.41%-0.59%)and 0.52%(95%CI: 0.44%-0.61%), respectively.Conclusion The escalating levels of ambient PM are positively associated with the increase of the hemorrhagic stroke morbidity in Shanghai, and the association is particularly stronger in females and people aged 66-85 years.关键词
颗粒污染物/出血性脑卒中/住院患者Key words
particulate matter/hemorrhagic stroke/inpatient分类
医药卫生引用本文复制引用
江波,牟喆,彭丽,张丽娟,李觉..上海市大气颗粒污染物对居民出血性脑卒中住院人数的影响[J].同济大学学报（医学版）,2017,38(3):115-119,5.基金项目
上海市气象与健康重点实验室开放基金(QXJK201503) （QXJK201503）
上海市卫生与计划生育委员会基金(201440312) （201440312）
