实用医学杂志2017，Vol.33Issue(14)：2329-2332,4.DOI:10.3969/j.issn.1006-5725.2017.14.020
耳鸣静息态磁共振局部一致性研究
Resting State Functional Magnetic Resonance Imaging of Tinnitus:Regional Homogeneity and Functional Connectivity
摘要
Abstract
Objective To explore the probable mechanism of tinnitus and the accompanied symptoms us-ing RS-FMRI. Methods We recruited 10 adults with chronic tinnitus and 10 health adults for fMRI in the resting state. Then we compared the differences of regional homogeneity(REHO)maps and functional connectivity to the whole-brain maps with the auditory cortex as a region of interest between the two groups. Results The REHO maps of tinnitus group showed significant differences in the automated anatomical labeling brain map including the middle frontal_gyrus (right),superior frontal_gyrus (left),entorhinal cortex_(right),middle occipital_gyrus (right),middle occipital gyrus(bilateral),lingual gyrus(left)and cuneate lobe(left). The functional connectivity maps of tinnitus group showed significant differences in lingal_gyrus(left)of AAL brain regions. The p threshold value was<0.001 in all results. Conclusion Tinnitus may cause abnormal neural activity in several non-auditory brain regions,which may be the neurophysiological mechanism of tinnitus accompanied symptoms.关键词
耳鸣/静息态磁共振/局部一致性/功能连接Key words
tinnitus/resting state MRI/regional homogeneity/functional connectivity引用本文复制引用
蔡伟伟,区洁楹,梁健刚,张涛..耳鸣静息态磁共振局部一致性研究[J].实用医学杂志,2017,33(14):2329-2332,4.基金项目
广州市番禺区科技计划项目(编号:2015-Z03-41) （编号:2015-Z03-41）
广州市番禺中心医院硕博基金项目(编号:2016-S-03) （编号:2016-S-03）
