中国组织工程研究2017，Vol.21Issue(19)：3051-3056,6.DOI:10.3969/j.issn.2095-4344.2017.19.016
腰椎QCT与骨质疏松性胸腰椎骨折伤椎骨造影弥散度的关联性
Relationship between the lumbar quantitative computed tomography values and contrast agent dispersion in osteoporotic thoracolumbar fractures
摘要
Abstract
BACKGROUND: Percutaneous vertebroplasty (PVP) is usually used for osteoporotic thoracolumbar fractures,which has various advantages such as easy to operate, short operation time, less trauma, rapid recovery,analgesic effect and so on. But its application is restricted due to nerve compression symptoms and pulmonary embolism caused by bone cement leakage. Thereafter, how to reduce the leakage of bone cement is an issue of concern.OBJECTIVE: To investigate the relationship between the lumbar quantitative computed tomography (QCT) values and contrast agent dispersion in osteoporotic thoracolumbar fractures. METHODS: Sixty cases of osteoporotic thoracolumbar fractures undergoing PVP were enrolled, and received QCT examination before surgery, and contrast agent was injected intraoperatively. X-ray examination was conducted to detect the bone mineral density, contrast agent dispersion and leakage of bone cement, and the relationship between the lumbar QCT values and contrast agent dispersion as well as leakage of bone cement.RESULTS AND CONCLUSION: (1) There were 110 vertebral fractures, and 74 vertebrae with contrast agent diffusing more than vertebral midline, accounting for 67.3%. There was significant difference in the contrast agent dispersion among groups (P < 0.05). (2) The bone cement leakage showed no significant difference among groups after injected with bone cement by unilateral or bilateral approach (P > 0.05). (3) These results suggest that contrast agent dispersion in osteoporotic thoracolumbar fractures has a certain relationship with the lumbar QCT values, and lumbar QCT values with more contrast agent dispersion, but the lumbar QCT values have no correlation with bone cement leakage. Therefore, choosing a appropriate approach based on the QCT values and contrast agent dispersion can reduce leakage and improve the safety of PVP.关键词
骨科植入物/脊柱植入物/骨质疏松/椎体骨折/腰椎QCT/对比剂弥散/骨水泥渗漏分类
医药卫生引用本文复制引用
宋泉生,许建文,唐福波,王晓琥,张家立,李智斐,饶远森,伍亮,邰志洪,覃海飚..腰椎QCT与骨质疏松性胸腰椎骨折伤椎骨造影弥散度的关联性[J].中国组织工程研究,2017,21(19):3051-3056,6.基金项目
广西科学研究与技术开发计划课题(桂科攻 10124001B-38) （桂科攻 10124001B-38）
广西壮族自治区卫生和计划生育委员会课题(合同号:Z2014119) （合同号:Z2014119）
广西中医药大学第一附属医院青年科学基金项目(GZYQJ2014016,GZYQJ2014015) （GZYQJ2014016,GZYQJ2014015）
the Research and Technology Development Program of Guangxi Zhuang Autonomous Region,No. 10124001B-38 （）
the Project of Health and Family Planning Commission of Guangxi Zhuang Autonomous Region, No. Z2014119 （）
the Scientific Foundation for the Youth of the Fist Affiliated Hospital of Guangxi University of Chinese Medicine, No. GZYQJ2014016 and GZYQJ2014015 （）
