股骨颈骨折内固定后股骨头坏死发生研究现状
Research progress of the osteonecrosis of the femoral head after internal fixation for femoral neck fractures
摘要
Abstract
BACKGROUND: Osteonecrosis of the femoral head (ONFH) following internal fixation of femoral neck fractures is difficult to be cured in clinic.OBJECTIVE: To analyze the literatures concerning ONFH in patients with femoral neck fractures treated with screw internal fixation in recent 15 years, and to summarize the research progress in views of epidemiology, etiology, diagnosis,treatment and rehabilitation.METHODS: Databases of CNKI, WanFang, CqVip, PubMed, Medline, Web of Science were searched with the keywords of "femoral neck fracture, osteonecrosis of femoral head, osteonecrosis, internal fixation, internal fixation with screw" in English and Chinese, respectively. Afterwards, the reviews and case reports were excluded. RESULTS AND CONCLUSION: (1) A total of 54 eligible articles addressing the ONFH following internal fixation for femoral neck fractures were included, and the incidence of ONFH varied from 8.1% to 37.2%, which was found at an average of 17 months after injury. (2) ONFH was found to be related to age, preoperative fracture displacement, preoperative traction,reduction condition, time from injury to operation, elderly patients companied with other diseases, older patients undergoing removal of the screws, closed or open internal fixation, restored time postoperatively, high body mass index, hyperlipidemia, season, and depression. (3) Early prevention and remedial surgery were used to treat ONFH. (4) The patients without weight-bearing activities at 3-6 months postoperatively could be beneficial for functional recovery. (5) These results suggest that choosing appropriate surgical programs and rehabilitation plan can reduce the incidence of ONFH and achieve good treatment outcomes, such as reasonable preoperative planning, standardized operation skills, correct diagnosis and treatment, proper postoperative rehabilitation and good doctor-patient cooperation.关键词
骨科植入物/关节植入物/股骨颈骨折/内固定/股骨头坏死/研究现状/国家自然科学基金分类
医药卫生引用本文复制引用
孙友强,陈雷雷,刘予豪,邹许亭,洪志楠,何伟..股骨颈骨折内固定后股骨头坏死发生研究现状[J].中国组织工程研究,2017,21(19):3095-3101,7.基金项目
广东省自然科学基金杰出青年基金(2015A03036037) （2015A03036037）
国家自然科学基金(81302990) （81302990）
广州中医药大学优秀博士论文培育项目 (GZYYB201602) （GZYYB201602）
广州中医药大学第一临床医学院优秀博士论文培育项目(YB201601) （YB201601）
广东省科技计划项目(2014A020221114) （2014A020221114）
广东省优势病种突破项目(粤中医函[2015]19 号) （粤中医函[2015]19 号）
the Natural Science Foundation for Distinguished Young Scholars of Guangdong Province,No. 2015A03036037 （）
the National Natural Science Foundation of China, No. 81302990 （）
the Excellent Doctoral Thesis Training Program of Guangzhou University of Chinese Medicine, No. GZYYB201602 （）
the Excellent Doctoral Thesis Training Drogram of the First Affiliated Hospital of Guangzhou University of Chinese Medicine, No. YB201601 （）
the Science and Technology Program of Guangdong Province, No. 2014A020221114 （）
the Superior Disease Breakthrough Project of Guangdong Province, No.[2015]19 （）
