烟草科技2017，Vol.50Issue(6)：53-60,8.
硅烷化-GC/MS联用测定卷烟主流烟气中7种酚类化合物
Determination of seven phenolic compounds in mainstream cigarette smoke by silanization-GC/MS
王加忠 1刘剑 1罗熹 1张丽 1姬厚伟 1赖东辉 1毛寒冰1
作者信息
- 1. 贵州中烟工业有限责任公司技术中心,贵阳市小河区开发大道96号 550009
- 折叠
摘要
Abstract
To determine seven phenolic compounds (phenol, o, m, p-cresol, o, m, p-dihydroxybenzene) in mainstream cigarette smoke accurately, a method was established by adopting N-methyl-N-(trimethylsilyl) trifluoroacetamide (MSTFA) silanization-GC/MS. The total particulate matters in mainstream smoke of two cigarettes were trapped by Cambridge filter pad under standard ISO smoking condition and extracted ultrasonically with chloroform for 10 min after adding internal standard (Phenol-d5). One mL extract was added to 30 μL MSTFA, followed by separation on a capillary column EIite-624 and analyzed by GC/MS after derivation for 20 min at 60 ℃. The results showed that: 1) The relative standard deviations (RSDs), recoveries and limits of quantitation (LOQs) of this method were 2.6%-5.6%, 93.1%-102.9% and 0.005-0.026 μg/cig, respectively. 2) Comparing with the standard method, m-cresol and p-cresol were completely separated by this method, which could determine the seven phenolic compounds in mainstream cigarette smoke accurately. 3) The data of 27 cigarette samples determined by the established method agreed well with those obtained by the standard method. This new method is stable, accurate, precise and of good repeatability, it is suitable for determining the seven phenolic compounds in mainstream cigarette smoke.关键词
硅烷化/气相色谱-质谱(GC/MS)/主流烟气/酚类化合物Key words
Silanization/Gas chromatography-mass spectrometry(GC/MS)/Mainstream cigarette smoke/Phenolic compound分类
轻工纺织引用本文复制引用
王加忠,刘剑,罗熹,张丽,姬厚伟,赖东辉,毛寒冰..硅烷化-GC/MS联用测定卷烟主流烟气中7种酚类化合物[J].烟草科技,2017,50(6):53-60,8.
