眼科新进展2017,Vol.37Issue(7):631-635,5.DOI:10.13389/j.cnki.rao.2017.0160
糖尿病患者视网膜血管血氧饱和度变化研究
Changes of retinal vessel oxygen saturation in diabetic patients
摘要
Abstract
Objective To observe the differences of retinal vessel oxygen saturation between diabetic and healthy subjects.Methods Seventy-one diabetic patients and 91 healthy persons were included diabetes group and control group respectively.Oxygen saturation was measured in retinal blood vessels in two groups using retinal Oxymap.The oxygen saturation in retinal arteries and veins about 1.5-3.0 disc-diameter from center of optic disc was analyzed by instrumental software.Results Among 71 cases of diabetics,there was no significant difference in retinal oxygen saturation between male and female,among different ages and duration of disorder (all P > 0.05).The retinal average arteriolar oxygen saturation in diabetes group was higher than that in control group (P =0.00).The diabetes group had the higher arteriolar oxygen saturation in all the quadrants,while only the superior temporal and inferior temporal showed significant difference statistically (all P <0.05).The retinal average venous oxygen saturation in diabetes group showed an upward trend although with no significance (P >0.05).Venous oxygen saturation in the diabetes group were higher in retinal superior temporal and inferior temporal quadrant and lower in retinal inferior nasal quadrant,there were significant statistical differences (all P < 0.05).The retinal arterio-venous oxygen saturation differences in diabetes group was higher than that in control group,there was significant statistical difference (P =0.00).Conclusion There is significant difference in retinal vessel oxygen saturation between diabetics and healthy subjects.There are different degrees of changes in retinal oxygen saturation among different quadrants,indicating uneven distribution of retinal oxygen metabolism in each quadrant.关键词
糖尿病/血氧饱和度/视网膜动脉/视网膜静脉Key words
diabetes mellitus/oxygen saturation/retinal artery/retinal vein分类
医药卫生引用本文复制引用
陈斐斐,钟鑫,段俊国..糖尿病患者视网膜血管血氧饱和度变化研究[J].眼科新进展,2017,37(7):631-635,5.基金项目
国家重大科学仪器设备开发专项(编号:2013YQ490859).Key Development Project of National Science Equipment (No:2013YQ490859) (编号:2013YQ490859)