眼科新进展2017，Vol.37Issue(7)：651-653,657,4.DOI:10.13389/j.cnki.rao.2017.0165
视网膜静脉阻塞黄斑水肿的多焦视网膜电图与光学相干断层扫描分析
Multifocal electroretinogram and optical coherence tomography characteristics of macular edema secondary to retinal vein occlusion
摘要
Abstract
Objective To investigate the characteristics of multifocal electroretinogram (mf-ERG) and optical coherence tomography (OCT) in macular edema (ME) secondary to retinal vein occlusion (RVO).Methods Mf-ERG and OCT were performed in 38 patients (38 eyes) of ME secondary from RVO patients and 23 normal persons (23 eyes) in the same period of the control group.OCT was used to detect macular retinal thickness (CMT) at foveal area with diameter 1 mm,mf-ERG was used to evaluate the function of macular retina and analyze the amplitude density of P1 wave and latency of P1,N1 wave from ring 1 to ring 5.Results Compared with the control group,the amplitude densities of P1 in BRVO group were obviously decreased in ring 2 (35.95 ± 17.04)nV · deg-2,ring 3(24.72 ±8.32)nV · deg-2,ring 4(19.28 ±6.38)nV ·deg-2,ring 5 (13.49-± 6.16) nV · deg-2,respectively (all P ＜ 0.05);The latencies of P1 were prolonged significantly in ring 2 (35.74-± 3.72) ms (P ＜ 0.05);The latencies of N1 were prolonged significantly in ring 2 (18.43-± 4.63) ms,ring 3 (18.67-± 2.86) ms (both P ＜ 0.05).Compared with the control group,the amplitude densities of P1 in CRVO group were obviously decreased in ring 1 (81.58 ± 43.15) nV · deg-2,ring 2 (33.71 ±9.81) nV · deg-2,ring 3 (22.15 ± 9.75) nV · deg-2,ring 4 (16.65-± 6.38) nV · deg-2,ring 5 (14.18-± 4.59) nV · deg-2,respectively (all P ＜ 0.05);The latencies of P1 were prolonged significantly in ring 2 (37.56 ± 5.55) ms,ring 3 (37.31 ± 5.22) ms,ring 4 (35.71 ±5.63) ms,ring 5 (37.30 ± 5.37) ms (all P ＜ 0.05);The latencies of N1 were prolonged significantly in ring 1 (21.82 ±5.76) ms,ring 2(19.18 ±4.82) ms,ring3 (19.31 ±4.25)ms,ring 4 (19.05 ± 4.55) ms,ring 5 (19.43 ± 4.12) ms (all P ＜ 0.05).There was negative correlation between CMT and amplitude densities of P1 of ring 1 in CRVO group (r =-0.576,P ＜ 0.05).Conclusion OCT combined with mf-ERG can comprehensively reflect the change of retinal fumction and structure in ME secondary to RVO.关键词
视网膜静脉阻塞/黄斑水肿/多焦视网膜电图/光学相干断层扫描Key words
retinal vein occlusion/macular edema/multifocal electroretinogram/optical coherence tomography分类
医药卫生引用本文复制引用
马为梅,雷晓琴,田芳,周荣乐..视网膜静脉阻塞黄斑水肿的多焦视网膜电图与光学相干断层扫描分析[J].眼科新进展,2017,37(7):651-653,657,4.基金项目
陕西省科技厅社会发展科技攻关项目(编号:2015SF232、2015SF085、2015SF106) （编号:2015SF232、2015SF085、2015SF106）
西安市科技局社会发展引导计划-医学研究项目[编号:SF1513(3)].Science and Technology Research Project of Shaanxi Provincial Science and Technology Department (No:2015SF232,2015SF085,2015SF106) （3）
Xi'an Municipal Science and Technology Bureau Social Development Guide Plan-Medical Research Project[No:SF1513(3)] （3）
