眼科新进展2017，Vol.37Issue(7)：654-657,4.DOI:10.13389/j.cnki.rao.2017.0166
无糖尿病视网膜病变糖尿病患者黄斑区视网膜厚度与病程及血糖水平的相关性研究
Correlation between macular thickness and course of disease, blood glucose level in patients with diabetic retinopathy without diabetes mellitus
摘要
Abstract
Objective To analyze the difference of macular retinal thickness between normal subjects and diabetic patients without retinopathy,and discuss the relationship between macular thickness and the course of diabetes,blood glucose level.Methods Twenty-two cases of patients with diabetic without retinopathy without retinopathy in our hospital of fourth Department of Internal medicine from April 2016 to November 2016 were selected as diabetic without retinopathy group,and another 22 normal pemons were selected as the normal group.The central subfield retinal thickness (CSRT),cube volume(CV) and cube average thickness(CAT) of all patients were determined by optical coherence tomography (OCT),and the difference of CSRT,CV and CAT between diabetic patients and normal group were analyzed.Then,the patients with diabetic retinopathy were sub-grouped according to the course of diabetes (group A,B,C,) and blood glucose status (group D and E),and the differences of CSRT,CV and CAT among them were compared.Results With the increase of diabetes duration in the diabetic without retinopathy group,CSRT,CV and CAT were gradually increased,and there was significant difference (P ＜ 0.05).With rising blood sugar in diabetics in the diabetic without retinopathy group,CSRT,CV and CAT were gradually increased,and there was significant difference (P ＜ 0.05).There were positive correlation between CSRT,CV,CAT and course,blood sugar of diabetes mellitus (all P ＜ 0.05).Conclusion Compared with normal population,CSRT,CV and CAT are significantly thickened in diabetes mellitus patients,and CSRT,CV and CAT are increased gradually with the increase of diabetes and blood glucose,which provide reliable reference for the diagnosis of early diabetic retinopathy.关键词
糖尿病/光学相干断层扫描/黄斑中心凹视网膜厚度/平均黄斑区厚度/黄斑部体积Key words
diabetes mellitus/optical coherence tomography/central subfield retinal thickness/mean macular thickness/macular volume分类
医药卫生引用本文复制引用
杨怡,李克勤,牛梅民,黄怀洁,张小娟,谢月书..无糖尿病视网膜病变糖尿病患者黄斑区视网膜厚度与病程及血糖水平的相关性研究[J].眼科新进展,2017,37(7):654-657,4.基金项目
佛山市自筹经费类科技创新项目(编号:2016 AB003283).Technological Innovation Self Financing Project of Foshan (No:2016AB003283) （编号:2016 AB003283）
