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灰度图像校正在视网膜内源光信号探测中的应用

张洁瑞 郭学谦 马丽萍 侯钧杰 邵双运

中国医疗设备2017,Vol.32Issue(7):51-55,5.
中国医疗设备2017,Vol.32Issue(7):51-55,5.DOI:10.3969/j.issn.1674-1633.2017.07.015

灰度图像校正在视网膜内源光信号探测中的应用

Application of Gray Image Level Correction in the Detection of Intrinsic Optical Signals in Retina

张洁瑞 1郭学谦 2马丽萍 2侯钧杰 1邵双运1

作者信息

  • 1. 北京交通大学 理学院,北京 100044
  • 2. 首都医科大学 生物医学工程学院,首都医科大学临床生物力学应用研究北京市重点实验室,北京 100069
  • 折叠

摘要

Abstract

Objective The image of intrinsic optical signals (IOSs) was preprocessed to eliminate the image position offset caused by the blink of the test eye and to reduce background noise caused by image gray level uneven. Methods We have adopted the normalized correlation coefficient of registration for image registration. Then, the gray linear transformation was used to obtain image gray scale correction. Finally we extracted IOSs of the macular area in retinal. Results Experimental results indicated that it could effectively improve the relative intensity of IOSs, trough amplitude was twice as high as the relative treatment (5% to 12%; 12% to 26%); in addition, we could observe more changes in signal details by improve the endogenous optical signal curve. Conclusion The results we get are similar to the results of existing literature. Thus, the method is effective and reliable, which lay a foundation for exploring signal physiology significance.

关键词

光学成像/灰度处理/内源光信号/信号探测/视网膜

Key words

optical imaging/gray scale/intrinsic optical signals/signal detection/retina

分类

医药卫生

引用本文复制引用

张洁瑞,郭学谦,马丽萍,侯钧杰,邵双运..灰度图像校正在视网膜内源光信号探测中的应用[J].中国医疗设备,2017,32(7):51-55,5.

基金项目

北京市教育委员会科技计划一般项目(KM201610025010). (KM201610025010)

中国医疗设备

OACSTPCD

1674-1633

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