中国感染控制杂志2017，Vol.16Issue(7)：593-595,3.DOI:10.3969/j.issn.1671-9638.2017.07.001
耐碳青霉烯类鲍曼不动杆菌目标性监测
Targeted surveillance on carbapenem-resistant Acinetobacter baumannii
摘要
Abstract
Objective To investigate the clinical distribution and antimicrobial resistance characteristics of carbapenem-resistant Acinetobacterbaumannii (CRAB).Methods CRAB isolated from all inpatients in a hospital in January-December 2015 were performed retrospective analysis,antimicrobial susceptibility testing result was analyzed.Results A total of 721 AB strains were detected,231 (32.04%)of which were CRAB,isolation rates of CRAB in quarter 1-4 were 48.99% (73/149),41.98%(68/162),27.39%(63/230),and 15.00%(27/180) respectively,which showed a decreased trend (P<0.001).CRAB mainly came from sputum specimen(n=140, 60.61%),followed by secretion of wound(n=33,14.28%)and urine specimen(n=24,10.39%).CRAB mainly distributed in intensive care unit,accounting for 43.72%(n=101),following by department of neurosurgery(n=37,16.02%),and burn/plastic surgery (n=22,9.52%).Resistance rates of CRAB to ampicillin/sulbactam, gentamicin,levofloxacin, and ciprofloxacin were 85.28% -90.48%,resistance rate to tobramycin was low (19.48%),no strains were found to be resistant to polymyxin B.Conclusion Antimicrobial resistance of CRAB is serious,it is necessary to focus on management of key departments,take scientific prevention and control measures, so as to effectively reduce the incidence of healthcare-associated infection.关键词
鲍曼不动杆菌/耐碳青霉烯鲍曼不动杆菌/CRAB/耐药性/监测Key words
Acinetobacter baumannii/carbapenem-resistant Acinetobacter baumannii/CRAB/drug resistance/microbial/surveillance分类
医药卫生引用本文复制引用
刘红梅,韩崇旭,朱小平,韩东升..耐碳青霉烯类鲍曼不动杆菌目标性监测[J].中国感染控制杂志,2017,16(7):593-595,3.基金项目
国家自然科学基金(NO:81400899) （NO:81400899）
