中国感染控制杂志2017，Vol.16Issue(7)：622-626,5.DOI:10.3969/j.issn.1671-9638.2017.07.007
呼吸机管路更换时间对VAP发病率影响的系统评价
Effect of ventilator circuit changes on incidence of ventilator-associated pneumonia:a systematic review
摘要
Abstract
Objective To evaluate systematically the effect of ventilator circuit changes on incidence of ventilator-associated pneumonia(VAP).Methods Literatures about the effect of ventilator circuit changes on occurrence of VAP were searched from PubMed,Cochrane Library,CNKI,VIP,and Wanfang database,incidence of VAP in pa-tients who received circuit changes at different intervals was compared,odds ratio (OR)and 95%CI were as effect index of the study,RevMan 5.2 software was used for data analysis.Results A total of 12 literatures were included,including 18003 patients using ventilators.According to the interval of ventilator circuit changes,patients were divided into 1-day group (n=191),2-day group(n=8932),3-day group(n=228),and 7-day group(n=8652).Meta analysis showed that circuit changed every 7 days had a lower risk of VAP than that changed once ev-ery day (OR,3.72[95%CI,1.50,9.23]),there was no significant difference in risk of VAP between 7-day group and 2-day group (OR,1.17[95%CI,1.00,1.37])as well as 7-day group and 3-day group(OR,0.77 [95%CI, 0.49,1 .23]).Conclusion Patients who received circuit changes every 7 days have a lower risk of developing VAP than those who received circuit changes once per day,so change the ventilator circuit in patients with mechanical ventilation every 7 days is more reasonable.关键词
呼吸机相关肺炎/肺炎/呼吸机相关/呼吸机管路/更换时间/系统评价/Meta分析Key words
ventilator-associated pneumonia/pneumonia/ventilator-associated/ventilator circuit/change inter-val/systematic review/Meta analysis分类
医药卫生引用本文复制引用
刘俊香,丁洪琼,汪芝碧..呼吸机管路更换时间对VAP发病率影响的系统评价[J].中国感染控制杂志,2017,16(7):622-626,5.基金项目
重庆市高等教育教学改革研究项目(133281) （133281）
