中国康复理论与实践2017，Vol.23Issue(7)：816-819,4.DOI:10.3969/j.issn.1006-9771.2017.07.017
A型肉毒毒素治疗痉挛型脑性瘫痪的疗效2年随访
Effect of Botulinum Toxin Type A on Spastic Cerebral Palsy:Two Years Follow-up
刘建军 1齐婧 2张雁 3曾凡勇 3李南玲 3席冰玉 3吴卫红3
作者信息
- 1. 首都医科大学康复医学院,北京市100068
- 2. 中国康复研究中心北京博爱医院,北京市100068
- 折叠
摘要
Abstract
Objective To investigate the long-term effect of Botulinum toxin type A (BTX-A) block on spasticity in cerebral palsy. Methods From June, 2005 to December, 2013, 51 children with spastic cerebral palsy accepted routine rehabilitation with (trial group, n=24) or without (control group, n=27) BTX-A block. They were assessed with modified Ashworth Scale (MAS), Physician Rating Scale (PRS) and Gross Motor Function Measure (GMFM) before treatment, and with PRS and GMFM two years after treatment. Results There was no significant difference between two groups in ages, body mass, and scores of MAS, PRS and GMFM before treatment (t<1.207,χ2=0.076, P>0.05). The scores of PRS and GMFM improved in both groups two years after treatment (t>2.217, P<0.05), and improved more in the trial group than in the control group (t>2.095, P<0.05). Conclusion The long-term effect of BTX-A block is positive. The rehabilitation training after block can promote their motor function recovery.关键词
脑性瘫痪/痉挛/神经阻滞/A型肉毒毒素/随访Key words
cerebral palsy/spasticity/nerve block/Botilinum toxin type A/follow-up分类
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刘建军,齐婧,张雁,曾凡勇,李南玲,席冰玉,吴卫红..A型肉毒毒素治疗痉挛型脑性瘫痪的疗效2年随访[J].中国康复理论与实践,2017,23(7):816-819,4.
