中国临床药理学杂志2017，Vol.33Issue(12)：1158-1160,3.DOI:10.13699/j.cnki.1001-6821.2017.12.023
血府逐瘀汤联合西药治疗老年难治性高血压的临床研究
Clinical trial of western medicine treatment combined with Xuefu Zhuyu decoction in the treatment elderly patients with refractory hypertension
摘要
Abstract
Objective To evaluate the clinical effect of Xuefu Zhuyu decoction combined with western medicine on elderly patients with refractory hypertension.Methods A total of 120 elderly patients with refractory hypertension were randomly divided into treatment group (n =60) and control group (n =60).Control group was given propranolol 5-10 mg orally,tid or qid;captopril 12.5 mg orally bid or tid;indapamide 2.5 mg orally qd.Treatment group was given Xuefu Zhuyu decoction 100 mL · d-1,bid on the basis of control group.All patients were treated for 90 d.The clinical symptoms and blood pressure were compared before and after treatment.Results The clinical efficacy was 95.00％ (57/60 cases) and 78.33％ (47/60 cases,P ＜0.05).After treatment,the systolic blood pressure (SBP) were (130.09 ±9.95),(113.08 ±15.24) mmHg in control group and treatment group,and diastolic blood pressure (DBP) were (84.40 ±9.05),(81.02 ±6.56) mmHg (P ＜0.05).There was 1 case of dizziness in control group,and no adverse drag reaction occurred in treatment group,with no significant difference (P ＞ 0.05).Conclusion Xuefu Zhuyu decoction combined with western medicine maybe an effective treatment on elderly patients with refractory hypertension.关键词
血府逐瘀汤/西药/难治性高血压Key words
Xuefu Zhuyu decoction/western medicine/refractory hypertension分类
医药卫生引用本文复制引用
王冠军,阮列敏,戴霓,季蕴辛,柴莹..血府逐瘀汤联合西药治疗老年难治性高血压的临床研究[J].中国临床药理学杂志,2017,33(12):1158-1160,3.基金项目
浙江省自然科学基金资助项目(LY14H090003) （LY14H090003）
