中国内镜杂志2017，Vol.23Issue(7)：46-49,4.DOI:10.3969/j.issn.1007-1989.2017.07.010
低剂量聚乙二醇联合抗坏血酸方案对肠道黏膜损伤的影响
Evaluating mucosal injuries of low-volume PEG plus ascorbic acid regimen in bowel preparation
任争 1杨德生 1侯洪涛 1孙金平 1康玉华 1丁春生1
作者信息
- 1. 河南大学淮河医院 消化内科,河南 开封 475000
- 折叠
摘要
Abstract
Objective To study the bowel-cleansing efficacy, patient security and mucosal injury of low-volume PEG plus ascorbic acid regimen. Methods Five hundred patients referred for colonoscopy were enrolled and randomly divided into two groups. Group A received low-volume PEG regimen, Group B received sodium phosphate (NaP) regimen for bowel preparation. Patients of the two groups drank solution 5 h before colonoscopies, serum creatinine and electrolyte were monitored at 5 h and 3 h before colonoscopies. The bowel-cleansing efficacy was rated during colonoscopy. All mucosal injuries observed during colonoscopy were biopsied and histopathologically reviewed. Results The patients of group A completed bowel preparation of 233 cases, completed colonoscopy 226 Cases, group B completed bowel preparation 238 cases, completed colonoscopy 210 cases. There was no significant difference in bowel cleansing between the groups (P > 0.05). Group A reported less incidence rate of the mucosal injuries than Group B. Group A reported better patient security than Group B at the same time. Conclusion Compared with sodium phosphate (NaP) regimen low-volume Polyethylene Glycol (PEG) plus ascorbic acid regimen exhibited equivalent bowel-cleansing efficacy and less incidence rate of the mucosal injuries and better patient security.关键词
低剂量聚乙二醇联合抗坏血酸/磷酸钠盐/肠道准备/肠道黏膜损伤Key words
polyethylene glycols/sodium phosphate/bowel preparation/mucosal injuries分类
医药卫生引用本文复制引用
任争,杨德生,侯洪涛,孙金平,康玉华,丁春生..低剂量聚乙二醇联合抗坏血酸方案对肠道黏膜损伤的影响[J].中国内镜杂志,2017,23(7):46-49,4.
