中国脑血管病杂志2017，Vol.14Issue(7)：356-362,7.DOI:10.3969/j.issn.1672-5921.2017.07.005
颅内大动脉狭窄患者Wingspan支架置入前后高分辨率核磁共振影像的变化
Changes of high-resolution magnetic resonance imaging before and after Wingspan stent in patients with intracranial large artery stenosis
摘要
Abstract
Objective To evaluate the imaging changes of the arterial wall and lumen at the site of intracranial large artery lesions with high-resolution magnetic resonance imaging (HR-MRI) before and after Wingspan stent implantation.Methods From December 2013 to December 2014,9 patients with symptomatic intracranial arterial stenosis (stenosis rate:70%-99%) admitted to the Department of Interventional Neuroradiology,Xuanwu Hospital,Capital Medical University were enrolled retrospectively.The sites of the lesions included middle cerebral arteries,basilar artery,and intracranial segment of vertebral artery.Head 3D HR-MRI technique was used to analyze and compare the changes of the tube-wall enhancement areas in the lesion sites through image registration and matching.The consistency of stenosis rates measured by HR-MRI and DSA was compared through Pearson correlation analysis and Bland-Altman Plot.Results The success rate of technique was 100% without related complications.(1) After Wingspan stent implantation,the gadolinium enhancement in the vascular walls of the stenosis sites was decreased significantly compared with that before procedure.The area of enhancement decreased was 87±16% after stent implantation compared with before implantation,and the difference was statistically significant (t=2.325,P=0.049).(2) Before stent implantation,the mean stenosis rates of the HR-MRI and DSA measurements were 82±6% and 82±8% respectively,and the difference was not statistically significant (t=0.051,P=0.961);after procedure,the mean stenosis rates of HR-MRI and DSA measurements were 16±12% and 21±12% respectively,and the difference was not statistically significant (t=1.345,P=0.216).(3) The Pearson correlation coefficients of HR-MRI and DSA for stenosis rate measurement before and after stent implantation were 0.347 (P=0.361) and 0.545 (P=0.129) respectively.Bland-Altman statistical images showed that most of the data points were within the consistency limit (x-±1.96 s).Conclusions As an in vivo noninvasive imaging means,HR-MRI can be used to assess the changes of vascular walls of the lesion sites,the vascular lumen,and the original plaques after the intracranial stent release.It can also be used to evaluate the reconstruction of intracranial arterial walls.关键词
症状性颅内动脉狭窄/Wingspan支架/高分辨率磁共振成像/颅内血管重建Key words
Symptomatic intracranial stenosis/Wingspan stent/High-resolution magnetic resonance imaging/Intracranial arterial remodeling引用本文复制引用
高鹏,杨旗,王亚冰,谌燕飞,马妍,赵国光,焦力群..颅内大动脉狭窄患者Wingspan支架置入前后高分辨率核磁共振影像的变化[J].中国脑血管病杂志,2017,14(7):356-362,7.基金项目
国家“十三五”重点研发计划(2016YFC1301700) （2016YFC1301700）
国家十二五科技支撑计划(2011BAI08B04) （2011BAI08B04）
北京市科技新星计划(2010B052) （2010B052）
