中国比较医学杂志2017，Vol.27Issue(7)：53-58,6.DOI:10.3969.j.issn.1671-7856.2017.07.010
公路运输对新西兰兔血液及生化指标的影响
Effects of road transport on hematological and biochemical parameters in new zealand rabbits
摘要
Abstract
Objective To observe the effects of road transport on hematological and biochemical parameters in New Zealand rabbits.Methods A total of 12 healthy New Zealand rabbits were selected for 2 h road transport.Blood samples were collected at 0, 24, 48, 72 and 96 h after transport, respectively.White blood cells (WBC), red blood cells (RBC), hemoglobin (HGB), hematocrit (MCV), mean erythrocyte hemoglobin content (MCH), mean erythrocyte hemoglobin concentration (MCHC) and platelets (PLT) were measured using a blood analyzer.Blood alanine aminotransferase (ALT), aspartate aminotransferase (AST), albumin (ALB), total protein (TP), urea nitrogen (UREA), creatinine, uric acid (UA), triglycerides (TG), total cholesterol (COHL), glucose (GLU), hypersensitive C-reactive protein (CRP), α-amylase (AMYL), and creatine kinase (CK) were detected by an automatic biochemical analyzer.Results Compared the parameters before and after transport, The WBC count was increased first (P< 0.05 or P < 0.01) and then decreased after transport, the levels of RBC, HGB, HCT and PLT were decreased first (P< 0.05 or P < 0.01) and then increased after transport, and MCV was significantly high at 96 h after transport (P< 0.05).Among the clinical biochemical parameters, ALT, AST and BUN were firstly elevated (P< 0.05 or P < 0.01) and then decreased.TP, ALB as well as CREA and TG were firstly decreased (P< 0.05 or P < 0.01) and then increased.GLU was significantly low at 24 h after transport (P< 0.05).All parameters except MCV at 96 h after transport were not significantly different from those before transport.Conclusions Changes of blood routine, liver and kidney function indexes, lipid metabolism indexes, glucose metabolism index and creatine kinase index are observed in the New Zealand rabbits after 2-hour road transportation, and all the indicators except MCV return to pre-transport levels within 96 h.关键词
公路运输/新西兰兔/血常规/生化指标Key words
Road transport/New zealand rabbits/Blood routine parameters/Clinical biochemical parameters分类
医药卫生引用本文复制引用
余传辛,高秀秀,万梓成,梁旺,王萧..公路运输对新西兰兔血液及生化指标的影响[J].中国比较医学杂志,2017,27(7):53-58,6.基金项目
广东省科技厅科技计划项目(2015A030302073) （2015A030302073）
广东省科技厅科技计划项目(2013B040200033). （2013B040200033）
