中国比较医学杂志2017，Vol.27Issue(7)：98-101,4.DOI:10.3969.j.issn.1671-7856.2017.07.018
大鼠心肌缺血模型制备方法的比较及改进浅析
Comparison and improvement of the methods for establishment of rat models of myocardial ischemia
摘要
Abstract
The method for preparation of models of myocardial ischemia in rats have been well described in the literature, are of practical value and have been chosen by many researchers for pharmacological studies of drugs for human diseases.However, there is still lack in some details of their operability and practicability.We re-selected the coronary artery ligation site, simplified the procedures and improved the experimental method for preparation of the models, and made satisfactory result.In this paper we will review the selection of method for preparing myocardial ischemia model in rats, describe some details of the surgical operation, explored the influencing factors and so on, and provide a reference for selecting most appropriate animal model in research.关键词
冠心病/心肌缺血/动物模型/方法/心脏/手术Key words
Coronary heart disease/Myocardial ischemia/Animal model/Establishment methods/Heart/Surgery分类
医药卫生引用本文复制引用
张世田,庞路路,唐汉庆,黄岑汉..大鼠心肌缺血模型制备方法的比较及改进浅析[J].中国比较医学杂志,2017,27(7):98-101,4.基金项目
国家自然科学基金项目(项目批准号81460658). （项目批准号81460658）
