中国实用妇科与产科杂志2017，Vol.33Issue(7)：746-750,5.DOI:10.19538/j.fk2017070122
康妇炎胶囊联合抗生素治疗盆腔炎性疾病随机对照研究
A randomized case-control study of Kangfuyan capsule plus antibiotics in treating pelvic inflammatory disease
曹远奎 1朱彩英 1李燕云 1陈丽梅 1刁文静 1谢锋 1郭奇桑 1宋昱 1隋龙1
作者信息
- 1. 复旦大学附属妇产科医院宫颈疾病诊疗中心上海市生殖内分泌重点实验室,上海200011
- 折叠
摘要
Abstract
Objective To evaluate the efficiency and the safety of Kangfuyan capsule plus antibiotics in treating pelvic inflammatory disease(PID).Methods The women with PID were recruited in the clinic of the Obstetrics and Gynecology Hospital of Fudan University from June 2014 to June 2016,then they were randomly divided into the experimental group(treated by Kangfuyan capsule plus antibiotics)and the control group(treated by antibiotics).The score of PID was evaluated before treatment and after treatment (3days,4 weeks,8weeks and 12weeks).Pelvic effusion was detected by ultrasound before treatment and after treatment (4 weeks,12weeks).The safety evaluation,including blood test,biochemical indicators,electrocardiogram and adverse effect,was performed before and 12 weeks after treatment.Results Both groups showed that the score of PID decreased significantly.The score of PID of the experimental group was statistically lower than the control group from 3 days to 12 weeks after treatment.The tenderness over the left adnexa in the experimental group was obviously better than the control group 12 weeks after treatment.The tenderness over the uterus in the experimental group was obviously better than the control group 8 and 12 weeks after treatment.The experimental group had less pelvic effusion than the control group 4 and 12 weeks after treatment.The efficiency of treatment was better in the experimental group compared with the control group (4,8 and 12 weeks after treatment).The experimental group had lower recurrent rate than the control group 12 weeks after treatment.Both groups had similar safety evaluation before and after treatment.Conclusion Kangfuyan capsule plus antibiotics can obviously improve the symptom of PID,decrease recurrence and the pelvic effusion.It' s safe in clinical use and its concrete mechanism needs further study.关键词
康妇炎胶囊/盆腔炎性疾病Key words
Kangfuyan capsule/pelvic inflammatory disease分类
医药卫生引用本文复制引用
曹远奎,朱彩英,李燕云,陈丽梅,刁文静,谢锋,郭奇桑,宋昱,隋龙..康妇炎胶囊联合抗生素治疗盆腔炎性疾病随机对照研究[J].中国实用妇科与产科杂志,2017,33(7):746-750,5.
