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从液体活检谈进展期胰腺癌的合理治疗

楼文晖 刘霄宇

中国实用外科杂志2017,Vol.37Issue(7):728-730,3.
中国实用外科杂志2017,Vol.37Issue(7):728-730,3.DOI:10.19538/j.cjps.issn1005-2208.2017.07.04

从液体活检谈进展期胰腺癌的合理治疗

Individualized treatment of advanced pancreatic carcinoma with special reference to liquid biopsy

楼文晖 1刘霄宇2

作者信息

  • 1. 复旦大学附属中山医院 普外科,上海200032
  • 2. 复旦大学附属中山医院 介入科,上海200032
  • 折叠

摘要

Abstract

The advantage of liquid biopsy in pancreatic cancer lies in minimal invasive, repeatable, and coherent to pathological diagnosis. Circulating tumor cells (CTCs) and Circulating cell-free DNA (cfDNA) are the major parts of liquid biopsy, there will be good perspertive in the personalized therapy of pancreatic cancer. Standardized technique, reasonable interpretation of the result will be the fundation of liquid biopsy in pancreatic cancer. Dynamically monitoring the change of CTC and cfDNA will provide clue for discovering new markers of recurrence and metastasis, as weill as new target of treatment.

关键词

进展期胰腺癌/液体活检/循环肿瘤细胞/循环游离DNA

Key words

advanced pancreatic carcinoma/liquid biopsy/circulating tumor cells/circulating cell-free DNA

分类

医药卫生

引用本文复制引用

楼文晖,刘霄宇..从液体活检谈进展期胰腺癌的合理治疗[J].中国实用外科杂志,2017,37(7):728-730,3.

中国实用外科杂志

OA北大核心CSCDCSTPCD

1005-2208

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