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枳椇皮提取物对肾结石大鼠的治疗作用

任群利 林冰 周英 卢凤羽 李文沛 俸婷婷

中国现代医学杂志2017,Vol.27Issue(14):24-27,4.
中国现代医学杂志2017,Vol.27Issue(14):24-27,4.DOI:10.3969/j.issn.1005-8982.2017.14.005

枳椇皮提取物对肾结石大鼠的治疗作用

Therapeutic effect of Hovenia acerba extract on renal calculi in rats

任群利 1林冰 2周英 2卢凤羽 2李文沛 1俸婷婷2

作者信息

  • 1. 贵州大学 生命科学学院,贵州 贵阳 550025
  • 2. 贵州大学药学院,贵州 贵阳 550025
  • 折叠

摘要

Abstract

Objective To study the therapeutic effect of intragastric administration of Hovenia acerba bark medicine on renal calculi in rats. Methods The rats were fed with ethylene alcohol and ammonium chloride to induce renal calculi and the effect of Hovenia acerba bark extract on renal calculi was studied. Results Hovenia acerba bark medicine had obvious effect on restoring the weight of rats with renal calculi, increasing the 24-h urinary output, promoting the excretion and metabolism of blood Ca2+, reducing the formation of renal calculi, the concentration of serum urea nitrogen and creatinine, slowing down the rat renal damage and disease caused by stones. Conclusions Hovenia acerba bark extract has certain therapeutic effect on rat kidney stones and its exact mechanism remains to be studied further.

关键词

枳椇皮提取物/肾结石模型/肾组织病理

Key words

Hovenia acerba extract/kidney stone model/kidney tissue pathology

分类

医药卫生

引用本文复制引用

任群利,林冰,周英,卢凤羽,李文沛,俸婷婷..枳椇皮提取物对肾结石大鼠的治疗作用[J].中国现代医学杂志,2017,27(14):24-27,4.

基金项目

贵州省教育厅自然科学研究基金[No:黔教科KY字(2015)369号] (2015)

贵州省科技计划[No:黔科合重大专项字(2015)6009-5] (2015)

中国现代医学杂志

OACSTPCD

1005-8982

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