中国药房2017，Vol.28Issue(20)：2750-2753,4.DOI:10.6039/j.issn.1001-0408.2017.20.04
广西9家"三甲"医院头孢菌素类抗菌药物对胆囊结石切除术患者住院费用和住院天数的影响分析
Influence Analysis of Cephalosporins Antibiotics on Cost and Length of Hospital Stay in Patients Under-went Gallbladder Calculus Resection from 9 Third Grade Class A Hospitals in Guangxi
摘要
Abstract
OBJECTIVE:To investigate the influence of cephalosporins antibiotics on cost and length of hospital stay in pa-tients underwent gallbladder calculus resection,and to provide reference for drug use in clinic. METHODS:A total of 1866 patients underwent gallbladder calculus resection were collected from 9 third grade class A hospitals in Guangxi during 2013-2014. SPSS 22.0 software was adopted to analyze cost and length of hospital stay in patients underwent gallbladder calculus resection. RESULTS:Multi-factor analysis showed that the factors which significantly affected the cost and length of hospital stay were antibiotics,hospi-tals,age,surgery types and disease species (all P<0.01). The antibiotics were divided into the subset 1-4 according to the cost of hospital stay:the subset 1 only contained cefuroxime(9454 yuan);the subset 2 contained noncephalosporins(16199 yuan)and ce-fazolin pentahydrate(17241 yuan);the subset 3 contained ceftazidime(20716 yuan),other cephalosporins(21046 yuan)and cefo-taxime sulbactam(22724 yuan);subset 4 contained cefotaxime sulbactam(22724 yuan),cefoperazone sulbactam(23688 yuan), cefoxitin(24685 yuan)and cefodizime(24698 yuan). The antibiotics were also divided into the subset 1-4 according to the length of hospital stay:the subset 1 only contained noncephalosporins (7.61 d);the subset 2 contained cefuroxime (8.94 d) and cefazolin pentahydrate(9.78 d);the subset 3 contained cefoxitin(13.39 d),cefodizime(13.44 d),other cephalosporins(14.32 d)and ceftazi-dime(14.60 d);the subset 4 included cefoperazone sulbactam(16.03 d)and cefotaxime sulbactam(16.91 d). The higher the subset numbers,the higher the cost of hospital stay or the longer the length of hospital stay;there were statistical differences among differ-ent subsets (P<0.05),while there was no statistical difference among the same subsets (P>0.05). CONCLUSIONS:Cephalospo-rins antibiotics can significantly influence the cost and length of hospital stay in patients underwent gallbladder calculus resec-tion. Antibiotics selection canbe considered comprehensively ac-cording to local medical resources and the patients'demands.关键词
胆囊结石/住院费用/住院天数/头孢菌素类抗菌药物Key words
Gallbladder calculus/Cost of hospital stay/Length of hospital stay/Cephalosporins antibitoics分类
医药卫生引用本文复制引用
杨玲玲,刘天奇,叶溪,莫志江..广西9家"三甲"医院头孢菌素类抗菌药物对胆囊结石切除术患者住院费用和住院天数的影响分析[J].中国药房,2017,28(20):2750-2753,4.基金项目
广西医疗卫生适宜技术研究与开发课题(No.S201420-02) （No.S201420-02）
