中国药房2017，Vol.28Issue(20)：2847-2851,5.DOI:10.6039/j.issn.1001-0408.2017.20.32
规范化药学服务对AECOPD患者临床治疗的干预效果评价
Evaluation of Intervention Effects of Standardized Pharmaceutical Care on Clinical Treatment of AECO-PD Patients
摘要
Abstract
OBJECTIVE:To evaluate the intervention effects of standardized pharmaceutical care on clinical treatment of acute exacerbation of chronic obstructive pulmonary disease(AECOPD)patients. METHODS:A total of 127 AECOPD patients were col-lected from respiratory medicine department of our hospital during Sept. 2014-Mar. 2015,and then divided into control group(63 cases)and observation group(64 cases)according to random number table. Control group only received traditional medical service and drug therapy. Observation group was additionally given standardized pharmaceutical care provided by clinical pharmacists ac-cording to AECOPD clinical pharmacy pathway on the basis of control group. The patients were followed up 1 month after dis-charge. The use of antibiotics during hospitalization,medication adherence,the occurrence of ADE,patient satisfaction and medica-tion bias during hospitalization and after discharge,the rates of ADR awareness and return visit after discharge were compared be-tween 2 groups. RESULTS:In both groups,1 patient withdrew from the study during hospitalitation;33 patients didn't complete return visit after discharge. During hospitalization,the rate of medication adherence and the total satisfaction of traditional medical procedures and medication guidance in observation group were significantly higher than control group;the utilization ratio of antibi-otics and combined use of antibiotics,AUD,the incidence of ADE,the proportion of medication bias were significantly lower than control group,with statistical significance(P<0.05). After discharge,the rate of ADR awareness and the total satisfaction of medi-cation guidance in observation group were significantly higher than control group,and the incidence of ADR was significantly low-er than control group,with statistical significance(P<0.05). There was no statistical significance in the rate of medication compli-ance,the rate of return visit,the proportion of medication bias between 2 groups after discharge(P>0.05). CONCLUSIONS:The standardized pharmaceutical care can significantly improve medication compliance and satisfaction of inpatients,contribute to ratio-nal use of antibiotics,reduce the incidence of ADE and medication bias,but have no significant effect on medication compliance, the rate of return visit and medication bias of discharged patients.关键词
临床药师/慢性阻塞性肺疾病急性加重期/药学服务/依从性/抗菌药物/药品不良事件/满意度Key words
Clinical pharmacist/AECOPD/Pharmaceutical care/Medication adherence/Antibiotics/ADE/Satisfaction分类
医药卫生引用本文复制引用
张立平,董华..规范化药学服务对AECOPD患者临床治疗的干预效果评价[J].中国药房,2017,28(20):2847-2851,5.基金项目
山东省药学会临床药学奥赛康中青年科研资助项目(No.Sdpa-ask-2014-10) （No.Sdpa-ask-2014-10）
